Biological activity of the multitargeted antifolate, MTA (LY231514), in human cell lines with different resistance mechanisms to antifolate drugs

被引：0
|
作者：
Schultz, RM [1 ]
Chen, VJ [1 ]
Bewley, JR [1 ]
Roberts, EF [1 ]
Shih, C [1 ]
Dempsey, JA [1 ]
机构：
[1] Eli Lilly & Co, Lilly Corp Ctr, Lilly Res Labs, Canc Res Div, Indianapolis, IN 46285 USA
来源：
SEMINARS IN ONCOLOGY | 1999年 / 26卷 / 02期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：68 / 73
页数：6
相关论文
共 50 条
  • [1] Overview of Phase I trials of multitargeted antifolate (MTA, LY231514)
    Rinaldi, DA
    SEMINARS IN ONCOLOGY, 1999, 26 (02) : 82 - 88
  • [2] Activity of the multitargeted antifolate LY231514 in the human tumor cloning assay
    Carolyn D. Britten
    Elzbieta Izbicka
    Susan Hilsenbeck
    Richard Lawrence
    Karen Davidson
    Caeser Cerna
    Lionel Gomez
    Eric K. Rowinsky
    Steven Weitman
    Daniel D. Von Hoff
    Cancer Chemotherapy and Pharmacology, 1999, 44 : 105 - 110
  • [3] Glutamyl hydrolase and the multitargeted antifolate LY231514
    Rhee, MS
    Ryan, TJ
    Galivan, J
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 1999, 44 (05) : 427 - 432
  • [4] Glutamyl hydrolase and the multitargeted antifolate LY231514
    Myung S. Rhee
    Thomas J. Ryan
    John Galivan
    Cancer Chemotherapy and Pharmacology, 1999, 44 : 427 - 432
  • [5] A practical synthesis of multitargeted antifolate LY231514
    Barnett, CJ
    Wilson, TM
    Kobierski, ME
    ORGANIC PROCESS RESEARCH & DEVELOPMENT, 1999, 3 (03) : 184 - 188
  • [6] Synthetic approaches to multitargeted antifolate LY231514
    Barnett, CJ
    Wilson, TM
    Kobierski, ME
    CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES 1997, 1997, : 123 - 126
  • [7] Activity of the multitargeted antifolate LY231514 in the human tumor cloning assay
    Britten, CD
    Izbicka, E
    Hilsenbeck, S
    Lawrence, R
    Davidson, K
    Cerna, C
    Gomez, L
    Rowinsky, EK
    Weitman, S
    Von Hoff, DD
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 1999, 44 (02) : 105 - 110
  • [8] Phase II studies in solid tumors with LY231514, a multitargeted antifolate (MTA)
    Thornton, DE
    John, W
    Loerher, P
    Eisenhauer, E
    CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES 1997, 1997, : 195 - 200
  • [9] Resistance to the multitargeted antifolate (MTA, LY231514): Multifactorial in human leukemia, breast, and colon carcinoma cells
    Schultz, RM
    Chen, VJ
    Bewley, JR
    Roberts, EF
    Shih, C
    Dempsey, JA
    ANNALS OF ONCOLOGY, 1998, 9 : 135 - 135
  • [10] Pemetrexed (Alimta, MTA, multitargeted antifolate, LY231514) for malignant pleural mesothelioma
    Manegold, C
    SEMINARS IN ONCOLOGY, 2003, 30 (04) : 32 - 36
12345