Objectives: To use goal attainment scaling (GAS) to measure clinically important functional change in persons with multiple sclerosis (MS) and to assess its responsiveness compared with standard measures used to evaluate progress in rehabilitation. Design: Prospective, observational cohort study. Setting: Tertiary inpatient rehabilitation unit in Victoria, Australia. Participants: Consecutive sample of 24 persons with MS admitted for comprehensive rehabilitation program. The male-to-female ratio was 10: 14, and the mean age +/- standard deviation was 52.0 +/- 1-8.3 years (range, 37-62y). Over half (n=14 [58.3%]) had secondary progressive MS. Interventions: Not applicable. Main Outcome Measures: GAS scores were calculated for 5 to 10 priority goals set prospectively by each patient in agreement with the multidisciplinary treating team and compared with standard outcome measures-the FIM instrument and Barthel Index-rated on admission and discharge from the program. Patients were categorized into responders and nonresponders based on an overall clinical global impression. Results: Of 203 selected goals, 167 were achieved at the predicted level. GAS recorded outcomes for 105 individualized goals not measured by the FIM and Barthel Index. Although all 3 measures showed statistically significant change from admission to discharge (P<.001), only GAS scores strongly correlated with the Clinical Global Impression scale (p=-.86, P<.001). GAS discharge scores differed significantly between the responder and nonresponder groups (Mann-Whitney, z=-3.78, P<.001). Different measures of effect size gave different results, but GAS was consistently more responsive than either the FIM or Barthel Index. Conclusions: This preliminary study suggests that GAS is a responsive and useful outcome measure for the rehabilitation of persons with MS, providing added value to standardized outcome measurement.
机构:
Med Univ South Carolina, Off Interprofess Initiat, Charleston, SC 29425 USAMed Univ South Carolina, Off Interprofess Initiat, Charleston, SC 29425 USA
Kascak, Kimberly
Keller, Everette
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Med Univ South Carolina, Dept Publ Hlth Sci, Charleston, SC 29425 USAMed Univ South Carolina, Off Interprofess Initiat, Charleston, SC 29425 USA
Keller, Everette
Dodds, Cindy
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Med Univ South Carolina, Coll Hlth Profess, Charleston, SC 29425 USAMed Univ South Carolina, Off Interprofess Initiat, Charleston, SC 29425 USA
机构:
French Red Cross, Lyon, France
French Red Cross, Massues Ctr, 92 Rue Edmond Locard, FR-69322 Lyon 05, FranceFrench Red Cross, Lyon, France
Bard-Pondarre, Rachel
Villepinte, Claire
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Univ Toulouse, Toulouse NeuroImaging Ctr, Toulouse, France
Toulouse Univ Hosp, Sch Occupat Therapy, Toulouse, FranceFrench Red Cross, Lyon, France
Villepinte, Claire
Roumenoff, Fabienne
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French Red Cross, Lyon, FranceFrench Red Cross, Lyon, France
Roumenoff, Fabienne
Lebrault, Helene
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St Maurice Hosp, Dept Congenital Neurol Dis, St Maurice, France
Sorbonne Univ, Biomed Imaging Lab, Paris, FranceFrench Red Cross, Lyon, France
Lebrault, Helene
Bonnyaud, Celine
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Hop Raymond Poincare, Dept Funct Invest, Mot Anal Lab, Garches, France
Univ Paris Saclay, Versailles, FranceFrench Red Cross, Lyon, France
Bonnyaud, Celine
Pradeau, Charles
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Clemenceau Inst, Phys Med & Rehabil Dept, Strasbourg, France
Strasbourg Univ Hosp, Strasbourg, FranceFrench Red Cross, Lyon, France
Pradeau, Charles
Bensmail, Djamel
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Hop Raymond Poincare, Rehabil Dept, Garches, France
Inserm, End Icap Lab, Versailles, FranceFrench Red Cross, Lyon, France
Bensmail, Djamel
Isner-Horobeti, Marie-Eve
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Clemenceau Inst, Phys Med & Rehabil Dept, Strasbourg, France
Strasbourg Univ Hosp, Strasbourg, France
Strasbourg Univ, Federat Translat Med Strasbourg, Strasbourg, FranceFrench Red Cross, Lyon, France
Isner-Horobeti, Marie-Eve
Krasny-Pacini, Agata
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Clemenceau Inst, Phys Med & Rehabil Dept, Strasbourg, France
Strasbourg Univ Hosp, Strasbourg, France
Strasbourg Univ, Cognit Neuropsychol & Pathophysiol Schizophrenia, Inserm, Strasbourg, FranceFrench Red Cross, Lyon, France