Tuberculosis screening after detection of a case in a paediatric haemato-oncology unit in a low prevalence country

被引：1
|
作者：
Grasa Lozano, Carlos Daniel [1 ,2 ,3 ]
Baro-Fernandez, Maria [4 ]
Rubio-San-Simon, Alba [4 ]
Blazquez-Gamero, Daniel [1 ,2 ]
Lopez-Roa, Paula [5 ]
Liebana, Constanza [6 ]
Guerra-Garcia, Pilar [4 ]
Moraleda, Cinta [1 ,2 ]
Epalza, Cristina [1 ,2 ]
机构：
[1] Univ Complutense Madrid, Hosp Univ 12 Octubre, Dept Paediat, Paediat Infect Dis Unit, Madrid, Spain
[2] Inst Invest Hosp 12 Octubre imas12, Madrid, Spain
[3] Hosp Univ La Paz, Dept Paediat, Paediat Infect Dis Unit, Madrid, Spain
[4] Univ Complutense Madrid, Hosp Univ 12 Octubre, Dept Paediat, Paediat Haemato Oncol Unit, Madrid, Spain
[5] Univ Complutense Madrid, Hosp Univ 12 Octubre, Microbiol Dept, Madrid, Spain
[6] Univ Complutense Madrid, Hosp Univ 12 Octubre, Paediat Radiol Unit, Madrid, Spain
来源：
ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA | 2022年 / 40卷 / 08期
关键词：
Tuberculosis; Haemato-oncology; Paediatrics; Screening; GAMMA RELEASE ASSAYS; MYCOBACTERIUM-TUBERCULOSIS; INFECTION; CHILDREN; DIAGNOSIS; ONCOLOGY;
D O I：
10.1016/j.eimc.2020.12.017
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Background: There are no guidelines to screen haemato-oncologic children when a tuberculosis (TB) outbreak is suspected. Methods: After exposition to an adult with active TB, children exposed from a haemato-oncology unit were screened according to immunosuppression status and time of exposure. Until an evaluation after 8-12 weeks from last exposure, isoniazid was indicated to those with negative initial work-up. Results: After 210 interventions, we detected a case of pulmonary TB, and another with latent TB infection. Pulmonary findings and treatment approach were challenging in some patients. Conclusions: The TB screening of oncologic children required a multidisciplinary approach, and clinicians managed challenging situations. (c) 2021 Sociedad Espanola de Enfermedades infecciosas y Microbiologia Clinica. Published by Elsievier Espana. S.L.U. All rights reserved.
引用
收藏
页码：423 / 427
页数：5
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