Two new species of Myrtaceae are described and illustrated, Calycolpus aequatorialis of Ecuador and Psidium huanucoense of Peru. Calycolpus aequatorialis appears to have a close relative in C. surinamensis, but differs in having a closed calyx, relatively little indumentum, and strongly 4-winged twigs. Psidium huanucoense is compared with the similar species P. acutangulum from which it differs in having velvety indumentum of short, yellowish, erect hairs and larger leaves. Comparison with P. guineense is also made, from which it differs in venation, number of ovules, anther length, and hair length.