Small-sized copolymeric nanoparticles for tumor penetration and intracellular drug release

被引：10
|
作者：
Zhu, Chun-Nan [1 ,2 ]
Zang, Liu-Yuan [1 ,2 ]
Zheng, Dong-Yun [1 ,2 ]
Cao, Hui-Min [1 ,2 ]
Liu, Xiao-Jun [1 ,2 ]
机构：
[1] South Cent Univ Nationalities, Coll Biomed Engn, Hubei Key Lab Med Informat Anal & Tumor Diag & Tr, Wuhan 430074, Peoples R China
[2] South Cent Univ Nationalities, Key Lab Cognit Sci, State Ethn Affairs Commiss, Wuhan 430074, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 13期
关键词：
POLYMERIC MICELLES; EFFICIENCY; SYSTEMS;
D O I：
10.1039/c9cc09716c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Poor solid-tumor penetration of nanocarriers limits the drug efficacy. Herein, small-sized copolymeric nanoparticles are prepared for delivering the chemotherapeutic drug DOX into solid tumors deeply and releasing the drug effectively. These small-sized copolymeric nanoparticles represent substantial potential for clinical translation.
引用
收藏
页码：2000 / 2003
页数：4
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