Analysis of Pilus Biogenesis Genes in Bacteria Expressing Type IV Pili

被引:0
|
作者
Ahmed, Saeed [1 ,2 ]
Ahmad, Ijaz [3 ,4 ]
Ahmad, Shakoor [3 ]
Shah, Zahir [3 ]
Shah, Muqadar [3 ]
Khan, Farhan Anwar [3 ]
Ahmad, Ijaz [3 ,4 ]
机构
[1] Huazhong Agr Univ, Natl Reference Lab Vet Drug Residue, Wuhan 430070, Hubei, Peoples R China
[2] Huazhong Agr Univ, MOA Key Lab Detect Vet Drugs Residues Foods, Wuhan 430070, Hubei, Peoples R China
[3] Univ Agr Peshawar, Dept Anim Hlth, Peshawar, Pakistan
[4] Univ Agr Peshawar, Dept Livestock Management Breeding & Genet, Peshawar, Pakistan
关键词
Type IV pilus genes; Sequence similarity; Pilus machinery; Schematic overview; PSEUDOMONAS-AERUGINOSA; NEISSERIA-MENINGITIDIS;
D O I
10.9775/kvfd.2018.19910
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The structural and sequences similarities of type-IV pili proteins were analysed in Pseudomonas aeruginosa, Vibrio cholerae, Neisseria meningitidis and Neisseria gonorrhoeae. Pathogenic Neisseria species possess pili-genes that code structural and assembly proteins of type-IV pili. A collection of assembly proteins reveal homology amongst P. aeruginosa and Neisseria. While in V. cholerae, these proteins ensure functional counterparts. The pilus retraction and assembly ATPases, PilB/PilF and PilT, PilU are homologous in Neisseria and P. aeruginosa, whereas V. cholerae holds only one ATPase called TcpT. In this work only type-IV pilus machinery of P. aeruginosa shows high likeness with pathogenic Neisseria.
引用
收藏
页码:125 / 128
页数:4
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