optoacoustics;
noninvasive monitoring;
total hemoglobin concentration;
clinical applications;
D O I:
10.1117/12.816005
中图分类号:
O43 [光学];
学科分类号:
070207 ;
0803 ;
摘要:
Existing techniques for total hemoglobin concentration [THb] monitoring are invasive and cannot be used continuously and in real time. We developed and built a novel, light-weight (2 lb), low-cost, optoacoustic system for noninvasive, accurate monitoring of [THb]. The system incorporates an optoacoustic probe designed for sensitive probing of blood vessels with high signal-to-noise ratio at low energy of laser diode pulses. We developed a new algorithm for accurate monitoring of [THb] in the radial artery with this system. We tested the system in human subjects with different [THb]. The studies confirmed the capability of the system to accurately monitor [THb].