Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7088 Danish whites

被引：2
|
作者：
Sparso, Thomas
Hussain, Meena Shaheen
Borch-Johnsen, Knut
Jorgensen, Torben
Madsbad, Sten
Hansen, Torben
Pedersen, Oluf
Andersen, Gitte
机构：
[1] Steno Diabet Ctr, DK-2820 Gentofte, Denmark
[2] Glostrup Univ Hosp, Res Ctr Prevent & Hlth, Glostrup, Denmark
[3] Univ Aarhus, Fac Hlth Sci, Aarhus, Denmark
[4] Hvidovre Univ Hosp, DK-2650 Hvidovre, Denmark
来源：
MOLECULAR GENETICS AND METABOLISM | 2007年 / 92卷 / 03期
关键词：
calsequestrin; type; 2; diabetes; obesity; association;
D O I：
10.1016/j.ymgme.2007.06.011
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Calsequestrin 1 (CASQ1) is a calcium storage protein of fast-twitch skeletal muscle cells. In previous human association studies the. results have been contradictory regarding the association between a CASQ1 rs2275703 polymorphism and type 2 diabetes. In the present study of the CASQ1 rs2275703 polymorphism in 7088 Danish whites the allele frequency and genotype distribution did not differ between type 2 diabetic patients and glucose-tolerant control subjects, neither was found any association with diabetes-related quantitative traits. (C) 2007 Elsevier Inc. All rights reserved.
引用
收藏
页码：278 / 282
页数：5
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