Does Urinary pH and Diet Influence the Rate of Urinary Tract Infection Recurrence After Electrofulguration in Women With Antibiotic-Recalcitrant Recurrent Urinary Tract Infections?

OBJECTIVES To assess if urine acidity may be preventative against urinary tract infection (UTIs) and affected by diet. Our goal was to evaluate the effect of urine pH on the rate of recurrent UTIs (RUTIs) after electrofulguration (EF) in 3 groups of women with different urine pH ranges as well as the relation between their diet composition and urine pH. METHODS In a prior IRB-approved prospective study, women recorded urinary pH 4 times a day and diet for a week. Three urinary pH groups were identified: never below 6, never above 6, and above and below 6. In this study, a 3-day diet analysis involved categorizing different foods by acidity based on pH food charts and calculating amounts consumed using a nutritional analysis database. Rate of UTIs after EF and urine pH after consumption of acidic foods was compared between urine pH groups. Our hypothesis was that low urinary pH protects against RUTIs. RESULTS Of 37/69 patients who underwent EF with long median follow-up duration (4-6 years), no difference was found among the groups for UTI frequency, rate, and culture characteristics. There was a no significant difference in the mean amount of acidic foods eaten and the urine pH after each meal as well as in total. CONCLUSIONS During long-term follow-up, no association was found between urine pH groups and acidic food intake, and rates of UTIs after EF, possibly because of no link between urine pH and UTIs or EF already provokes an important reduction in rates of UTIs. (C) 2022 Elsevier Inc.