Protein Kinase C-Mediated Cardiac Troponin I S43/45 Phosphorylation Causes Contractile Dysfunction in Human Heart Failure and in Rodents

被引：0

作者：

Ravichandran, Vani S. ^{[1
]}

Schatz, Tabea M. ^{[1
]}

Westfall, Margaret V. ^{[2
]}

机构：

[1] Univ Michigan, Cellular & Mol Biol, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Dept Cardiac Surg, Ann Arbor, MI 48109 USA

来源：

BIOPHYSICAL JOURNAL | 2019年 / 116卷 / 03期

关键词：

D O I：

10.1016/j.bpj.2018.11.200

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

148-Plat

引用

下载

页码：29A / 29A

页数：1

共 23 条

[1] Cardiac contractile dysfunction and protein kinase C-mediated myofilament phosphorylation in disease and aging
Ravichandran, Vani S.
Patel, Himanshu J.
Pagani, Francis D.
Westfall, Margaret, V
JOURNAL OF GENERAL PHYSIOLOGY, 2019, 151 (09): : 1070 - 1080
[2] Role of troponin I phosphorylation in protein kinase C-mediated enhanced contractile performance of rat myocytes
Westfall, MV
Borton, AR
JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (36) : 33694 - 33700
[3] Protein kinase C-mediated phosphorylation of troponin I domains in adult cardiac myocytes.
Westfall, MV
BIOPHYSICAL JOURNAL, 2000, 78 (01) : 365A - 365A
[4] Differential role of troponin I residues in the protein kinase C-mediated contractile response to endothelin
Robinson, D
Westfall, M
BIOPHYSICAL JOURNAL, 2004, 86 (01) : 394A - 394A
[5] Novel Cardiac Troponin I S43/45N Substitution does not Cause Aberrant Cardiac Remodeling or Dysfunction in Mice
Ravichandran, Vani S.
Westfall, Margaret V.
Schatz, Tabea M.
BIOPHYSICAL JOURNAL, 2021, 120 (03) : 342A - 342A
[6] Protein Kinase C-Induced Troponin I Phosphorylation Causes Changes in Cardiac Contractile Function but not the Intracellular Calcium Transient
Kirk, Jonathan A.
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CIRCULATION, 2008, 118 (18) : S544 - S544
[7] Protein kinase C-mediated phosphorylation of HIV-I Nef in human cell lines
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Harris, MPG
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (19) : 12289 - 12294
[8] Partial replacement of cardiac troponin I with a non-phosphorylatable mutant at serines 43/45 attenuates the contractile dysfunction associated with PKCε phosphorylation
Scruggs, SB
Walker, LA
Lyu, T
Geenen, DL
Solaro, RJ
Buttrick, PM
Goldspink, PH
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2006, 40 (04) : 465 - 473
[9] A critical role for troponin I serines 43/45 in the regulation of cardiac myofilament function by protein kinase C
Pyle, WG
Koretsky, AP
Del Nido, PJ
Solaro, RJJ
De Tombe, PP
CIRCULATION, 2001, 104 (17) : 314 - 314
[10] Influence of troponin I phosphorylation by endothelin-activated protein kinase C on adult cardiac myocyte contractile function
Westfall, M
Burton, AR
BIOPHYSICAL JOURNAL, 2002, 82 (01) : 396A - 396A

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