Cytorhizophins A and B, benzophenone-hemiterpene adducts from the endophytic fungus Cytospora rhizophorae

被引：27

作者：

Liu, Hongxin ^{[1
]}

Tan, Haibo ^{[2
]}

Wang, Wenxuan ^{[3
]}

Zhang, Wenge ^{[2
]}

Chen, Yuchan ^{[1
]}

Li, Saini ^{[1
]}

Liu, Zhaoming ^{[1
]}

Li, Haohua ^{[1
]}

Zhang, Weimin ^{[1
]}

机构：

[1] Guangdong Inst Microbiol, Guangdong Prov Key Lab Microbial Culture Collect, Guangdong Open Lab Appl Microbiol, State Key Lab Appl Microbiol Southern China, Guangzhou 510070, Guangdong, Peoples R China

[2] Chinese Acad Sci, Key Lab Plant Resources Conservat & Sustainable U, Guangdong Prov Key Lab Appl Bot, Program Nat Prod Chem Biol,South China Bot Garden, Guangzhou 510650, Guangdong, Peoples R China

[3] South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Hubei, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2019年 / 6卷 / 05期

基金：

中国国家自然科学基金;

关键词：

A-C; DERIVATIVES;

D O I：

10.1039/c8qo01306c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A pair of novel enantiomeric benzophenone-hemiterpene adducts, (+)-cytorhizophin A (1a) and (-)-cytorhizophin A (1b) as well as cytorhizophin B (2), all of them featuring an unprecedented 6/ 7/ 6/ 7 tetracyclic fused ring system, together with their biosynthetically related precursor cytorhizophin C (3) were isolated from Cytospora rhizophorae A761. Their structures were fully characterized on the basis of extensive spectroscopic analysis, with the absolute configurations of 1 determined by X-ray diffraction and electronic circular dichroism (ECD) calculations. Moreover, compounds 1-3 were evaluated for in vitro antimicrobial activity.

引用

页码：591 / 596

页数：6

共 50 条

[1] Polyketones from the endophytic fungus Cytospora rhizophorae
Liu, Hongxin
Liu, Zhaoming
Chen, Yuchan
Tan, Haibo
Zhang, Wenge
Zhang, Weimin
NATURAL PRODUCT RESEARCH, 2023, 37 (07) : 1053 - 1059
[2] Cytosporins A-D, novel benzophenone derivatives from the endophytic fungus Cytospora rhizophorae A761
Liu, Hong-Xin
Tan, Hai-Bo
Chen, Kai
Zhao, Li-Yun
Chen, Yu-Chan
Li, Sai-Ni
Li, Hao-Hua
Zhang, Wei-Min
ORGANIC & BIOMOLECULAR CHEMISTRY, 2019, 17 (09) : 2346 - 2350
[3] Pyrone and isocoumarin derivatives from the endophytic fungus Cytospora rhizophorae
Liu, Hongxin
Zhang, Yanjiang
Chen, Yuchan
Liu, Zhaoming
Tan, Haibo
Zhang, Weimin
ORGANIC & BIOMOLECULAR CHEMISTRY, 2022, 20 (24) : 4900 - 4904
[4] Alkyl aromatic derivatives from the endophytic fungus Cytospora rhizophorae
Zhang, Yanjiang
Liu, Hongxin
Chen, Yuchan
Liu, Zhaoming
Qiu, Kaidi
Wei, Shanshan
Zhang, Weimin
Tan, Haibo
JOURNAL OF ANTIBIOTICS, 2023, 76 (03): : 121 - 130
[5] Alkyl aromatic derivatives from the endophytic fungus Cytospora rhizophorae
Yanjiang Zhang
Hongxin Liu
Yuchan Chen
Zhaoming Liu
Kaidi Qiu
Shanshan Wei
Weimin Zhang
Haibo Tan
The Journal of Antibiotics, 2023, 76 : 121 - 130
[6] Rhizophols A and B, antioxidant and axially chiral benzophenones from the endophytic fungus Cytospora rhizophorae
Liu, Zhaoming
Tan, Haibo
Chen, Kai
Chen, Yuchan
Zhang, Wenge
Chen, Shanchong
Liu, Hongxin
Zhang, Weimin
ORGANIC & BIOMOLECULAR CHEMISTRY, 2019, 17 (47) : 10009 - 10012
[7] Cytospones E-J from the endophytic fungus Cytospora rhizophorae
Zhang, Yanjiang
Liu, Hongxin
Chen, Yuchan
Wei, Shanshan
Zhang, Weimin
Tan, Haibo
FITOTERAPIA, 2022, 163
[8] Three new highly-oxygenated metabolites from the endophytic fungus Cytospora rhizophorae A761
Liu, Hong-Xin
Tan, Hai-Bo
Liu, Yuan
Chen, Yu-Chan
Li, Sai-Ni
Sun, Zhang-Hua
Li, Hao-Hua
Qiu, Sheng-Xiang
Zhang, Wei-Min
FITOTERAPIA, 2017, 117 : 1 - 5
[9] Antioxidant Aryl-Substituted Phthalan Derivatives Produced by Endophytic Fungus Cytospora rhizophorae
Liu, Hongxin
Liu, Zhaoming
Zhang, Yanjiang
Chen, Yuchan
Wang, Huan
Tan, Haibo
Zhang, Weimin
FRONTIERS IN CHEMISTRY, 2022, 10
[10] Cytorhizins A-D, Four Highly Structure-Combined Benzophenones from the Endophytic Fungus Cytospora rhizophorae
Liu, Hongxin
Tan, Haibo
Chen, Yuchan
Guo, Xueying
Wang, Wenxuan
Guo, Heng
Liu, Zhaoming
Zhang, Weimin
ORGANIC LETTERS, 2019, 21 (04) : 1063 - 1067

← 1 2 3 4 5 →