ESPAC-4: A Multicenter, International, Randomized Controlled Phase III Trial of Adjuvant Combination Chemotherapy of Gemcitabine (GEM) and Capecitabine (CAP), Versus Monotherapy Gemcitabine in Patients With Resected Pancreatic Ductal Adenocarcinoma

被引：0

作者：

Neoptolemos, J. P. ^{[1
]}

Palmer, D. ^{[1
]}

Ghaneh, P. ^{[1
]}

Valle, J. ^{[2
,3
]}

Cunningham, D. ^{[4
]}

Wadsley, J. ^{[5
]}

Meyer, T. ^{[6
]}

Anthoney, A. ^{[7
]}

Glimelius, B. ^{[8
]}

Falk, S. ^{[9
]}

Lind, P. ^{[10
]}

Izbicki, J. ^{[11
]}

Middleton, G. ^{[12
]}

Ross, P. ^{[13
]}

Wasan, H. ^{[14
]}

McDonald, A. ^{[15
]}

Crosby, T. ^{[16
]}

Psarelli, E. ^{[1
]}

Hammel, P. ^{[17
]}

Buechler, M. W. ^{[18
]}

机构：

[1] Univ Liverpool, Liverpool, Merseyside, England

[2] Univ Manchester, Manchester, Lancs, England

[3] Christie, Manchester, Lancs, England

[4] Royal Marsden Hosp, London, England

[5] Weston Pk Hosp, Sheffield, S Yorkshire, England

[6] Royal Free Hosp, London, England

[7] St James Univ Hosp, Leeds, W Yorkshire, England

[8] Uppsala Univ, Uppsala, Sweden

[9] Bristol Haematol & Oncol Ctr, Bristol, Avon, England

[10] Karolinska Univ Hosp, Stockholm, Sweden

[11] Univ Hamburg, Med Inst UKE, Hamburg, Germany

[12] Royal Surrey Cty Hosp, Guildford, Surrey, England

[13] Guys Hosp, London, England

[14] Hammersmith Hosp, London, England

[15] Beatson West Scotland Canc Ctr, Glasgow, Lanark, Scotland

[16] Velindre Hosp, Cardiff, S Glam, Wales

[17] Hop Beaujon, Clichy, France

[18] Heidelberg Univ, Heidelberg, Germany

来源：

PANCREAS | 2016年 / 45卷 / 10期

关键词：

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

引用

页码：1529 / 1529

页数：1

共 50 条

[1] ESPAC-4: A multicenter, international, open-label randomized controlled phase III trial of adjuvant combination chemotherapy of gemcitabine (GEM) and capecitabine (CAP) versus monotherapy gemcitabine in patients with resected pancreatic ductal adenocarcinoma.
Neoptolemos, John P.
Palmer, Dan
Ghaneh, Paula
Valle, Juan W.
Cunningham, David
Wadsley, Jonathan
Meyer, Tim
Anthoney, Alan
Glimelius, Bengt
Falk, Stephen
Segersvard, Ralf
Izbicki, Jakob R.
Middleton, Gary William
Ross, Paul J.
Wasan, Harpreet
Mcdonald, Alec
Crosby, Tom David Lewis
Psarelli, Eftychia Eirini
Hammel, Pascal
Buchler, Markus W.
JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (18)
[2] ESPAC-4: A multicenter, international, open-label randomized controlled phase III trial of adjuvant combination chemotherapy of gemcitabine (GEM) and capecitabine (CAP) versus monotherapy gemcitabine in patients with resected pancreatic ductal adenocarcinoma: Five year follow-up.
Neoptolemos, John P.
Palmer, Daniel H.
Ghaneh, Paula
Valle, Juan W.
Cunningham, David
Wadsley, Jonathan
Meyer, Tim
Anthoney, Alan
Glimelius, Bengt
Falk, Stephen
Segersvard, Ralf
Middleton, Gary William
Ross, Paul J.
Wasan, Harpreet Singh
McDonald, Alec
Crosby, Tom David Lewis
Psarelli, Eftychia Eirini
Hammel, Pascal
Hackert, Thilo
Buchler, Markus W.
JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
[3] Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial
Neoptolemos, John P.
Palmer, Daniel H.
Ghaneh, Paula
Psarelli, Eftychia E.
Valle, Juan W.
Halloran, Christopher M.
Faluyi, Olusola
O'Reilly, Derek A.
Cunningham, David
Wadsley, Jonathan
Darby, Suzanne
Meyer, Tim
Gillmore, Roopinder
Anthoney, Alan
Lind, Pehr
Glimelius, Bengt
Falk, Stephen
Izbicki, Jakob R.
Middleton, Gary William
Cummins, Sebastian
Ross, Paul J.
Wasan, Harpreet
McDonald, Alec
Crosby, Tom
Ma, Yuk Ting
Patel, Kinnari
Sherriff, David
Soomal, Rubin
Borg, David
Sothi, Sharmila
Hammel, Pascal
Hackert, Thilo
Jackson, Richard
Buechler, Markus W.
LANCET, 2017, 389 (10073): : 1011 - 1024
[4] Evaluation of the prognostic role of aspirin and metformin in the ESPAC 4 randomised trial of adjuvant gemcitabine versus gemcitabine plus capecitabine in patients with resected pancreatic cancer
Ponweera, Arachchige
Robinson, Matthew
Jackson, Richard
Halloran, Chris
Palmer, Dan
Hackert, Thilo
Costello, Eithne
Greenhalf, Bill
Buechler, Markus
Neoptolemos, John
Ghaneh, Paula
BRITISH JOURNAL OF SURGERY, 2022, 109
[5] Patterns of Recurrence After Resection of Pancreatic Ductal Adenocarcinoma (PDAC) in the ESPAC-4 Randomized Adjuvant Chemotherapy Trial
Neoptolemos, J. P.
Jones, R. P.
Psarelli, E. E.
Jackson, R.
Ghaneh, P.
Halloran, C. M.
Palmer, D. H.
Tjaden, C.
Strobel, O.
Hackert, T.
Buechler, M. W.
PANCREAS, 2019, 48 (10) : 1497 - 1498
[6] ESPAC-3(v2): A multicenter, international, open-label, randomized controlled phase III trial of adjuvant 5-fluorouracil/folinic acid (5-FU/FA) versus gemcitabine (GEM) in patients with resected pancreatic ductal adenocarcinoma
Neoptolemos, J.
Buechler, M.
Stocken, D. D.
Ghaneh, P.
Smith, D.
Bassi, C.
Moore, M.
Cunningham, D.
Dervenis, C.
Goldstein, D.
JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (15)
[7] ESPAC-3(v2): A multicenter, international, open-label, randomized, controlled phase III trial of adjuvant 5-fluorouracil/folinic acid (5-FU/FA) versus gemcitabine (GEM) in patients with resected pancreatic ductal adenocarcinoma
Neoptolemos, J.
Buechler, M.
Stocken, D. D.
Ghaneh, P.
Smith, D.
Bassi, C.
Moore, M.
Cunningham, D.
Dervenis, C.
Goldstein, D.
JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (18)
[8] Phase III randomised comparison of gemcitabine (GEM) versus gemcitabine plus capecitabine (GEM-CAP) in patients with advanced pancreatic cancer
不详
EJC SUPPLEMENTS, 2005, 3 (04): : 12 - 12
[9] Unicancer GI PRODIGE 24/CCTG PA.6 trial: A multicenter international randomized phase III trial of adjuvant mFOLFIRINOX versus gemcitabine (gem) in patients with resected pancreatic ductal adenocarcinomas.
Conroy, Thierry
Hammel, Pascal
Hebbar, Mohamed
Ben Abdelghani, Meher
Wei, Alice Chia-chi
Raoul, Jean-Luc
Chone, Laurence
Francois, Eric
Artru, Pascal
Biagi, James Joseph
Lecomte, Thierry
Assenat, Eric
Faroux, Roger
Ychou, Marc
Volet, Julien
Sauvanet, Alain
Jouffroy-Zeller, Claire
Rat, Patrick
Castan, Florence
Bachet, Jean-Baptiste
JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (18)
[10] A Randomized Phase II Trial of Adjuvant Chemotherapy With Uracil/Tegafur and Gemcitabine Versus Gemcitabine Alone in Patients With Resected Pancreatic Cancer
Yoshitomi, Hideyuki
Togawa, Akira
Kimura, Fumio
Ito, Hiroshi
Shimizu, Hiroaki
Yoshidome, Hiroyuki
Otsuka, Masayuki
Kato, Atsushi
Nozawa, Satoshi
Furukawa, Katsunori
Miyazaki, Masaru
CANCER, 2008, 113 (09) : 2448 - 2456

← 1 2 3 4 5 →