Genotypic characterization of sequential Aspergillus fumigatus isolates from patients with cystic fibrosis

被引:57
|
作者
Verweij, PE [1 ]
Meis, JFGM [1 ]
Sarfati, J [1 ]
HoogkampKorstanje, JAA [1 ]
Latge, JP [1 ]
Melchers, WJG [1 ]
机构
[1] INST PASTEUR,ASPERGILLUS LAB,PARIS,FRANCE
关键词
D O I
10.1128/JCM.34.10.2595-2597.1996
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Twenty-three sequential Aspergillus fumigatus sputum isolates, which had been collected over a period of 2 years, from two patients with cystic fibrosis were genotyped by random amplified polymorphic DNA PCR and restriction fragment length polymorphism analysis. In patient B, one genotype was predominantly present in the sputum samples, while in the other patient up to nine different genotypes were identified. This study suggests that different patterns of colonization with A, fumigatus exist in patients with cystic fibrosis.
引用
收藏
页码:2595 / 2597
页数:3
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