Tumor reduction by a small molecule human PD-1/PD-L1 inhibitor in a melanoma/PBMC co-implantation model.

被引：0

作者：

Vilalta, Marta ^{[1
]}

Punna, Sreenivas ^{[1
]}

Li, Shijie Chris ^{[1
]}

Malathong, Viengkham ^{[1
]}

Lange, Christopher ^{[1
]}

McMurtrie, Darren ^{[1
]}

Yang, Ju ^{[1
]}

Roth, Howard ^{[1
]}

McMahon, Jeffrey ^{[1
]}

Campbell, James J. ^{[1
]}

Ertl, Linda S. ^{[1
]}

Ong, Ryan ^{[1
]}

Wang, Yu ^{[1
]}

Zhao, Niky ^{[1
]}

Chhina, Vicky ^{[1
]}

Kumamoto, Alice ^{[1
]}

Yau, Simon ^{[1
]}

Dang, Tong ^{[1
]}

Zhang, Penglie ^{[1
]}

Schall, Thomas J. ^{[1
]}

Singh, Rajinder ^{[1
]}

机构：

[1] ChemoCentryx, Mountain View, CA USA

来源：

CANCER IMMUNOLOGY RESEARCH | 2020年 / 8卷 / 04期

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

B26

引用

页码：95 / 95

页数：1

共 50 条

[1] In vitro characterization of a small molecule PD-1 inhibitor that targets the PD-l/PD-L1 interaction
Lu, Chih-Hao
Chung, Wei-Min
Tsai, Chun-Hao
Cheng, Ju-Chien
Hsu, Kai-Cheng
Tzeng, Huey-En
SCIENTIFIC REPORTS, 2022, 12 (01)
[2] In vitro characterization of a small molecule PD-1 inhibitor that targets the PD-l/PD-L1 interaction
Chih-Hao Lu
Wei-Min Chung
Chun-Hao Tsai
Ju-Chien Cheng
Kai-Cheng Hsu
Huey-En Tzeng
Scientific Reports, 12
[3] A small molecule human PD-1/PD-L1 inhibitor promotes T cell immune activation and reduces tumor growth in a preclinical model
Colomer, M. Vilalta
Punna, S.
Li, S.
Malathong, V.
Lange, C.
McMurtrie, D.
Yang, J.
Roth, H.
McMahon, J.
Campbell, J. J.
Ertl, L. S.
Ong, R.
Wang, Y.
Zhao, N.
Yau, S.
Dang, T.
Zhang, P.
Schall, T. J.
Singh, R.
ANNALS OF ONCOLOGY, 2018, 29
[4] A Small Molecule Antagonist of PD-1/PD-L1 Interactions Acts as an Immune Checkpoint Inhibitor for NSCLC and Melanoma Immunotherapy
Wang, Yuanyuan
Gu, Tingxuan
Tian, Xueli
Li, Wenwen
Zhao, Ran
Yang, Wenqian
Gao, Quanli
Li, Tiepeng
Shim, Jung-Hyun
Zhang, Chengjuan
Liu, Kangdong
Lee, Mee-Hyun
FRONTIERS IN IMMUNOLOGY, 2021, 12
[5] PD-1 and PD-L1 antibodies for melanoma
Tsai, Katy K.
Zarzoso, Ines
Daud, Adil I.
HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2014, 10 (11) : 3111 - 3116
[6] Small-molecule inhibitor PD-1 /PD-L1 interaction for colorectal cancer treatment
Anaya-Ruiz, Maricruz
Perez-Santos, Martin
PHARMACEUTICAL PATENT ANALYST, 2021, 10 (06) : 245 - 250
[7] Novel, small molecule inhibitors of PD-1/PD-L1 pathway
Rastelli, Luca
Rajagopal, Sridharan
Gajendran, Chandru
Sadhu, Naveen M.
Mohd, Zainuddin
Gosu, Ramachandraiah
Friedmann-Morvinski, Dinorah
Kandan, Saravanan
Birudukota, Swarnakumari
Srinivasan, S.
Krishnakumar, V
Wahid, Saif
Siddiqui, Amir
Viswakarma, Santosh
Narayan, Ashwini
Rudresh, G.
Mullurwar, Sadanand R.
Sher, Divsha
Mansur, Shahar
Sivanandhan, Dhanalakshmi
JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)
[8] Small molecule PD-L1 inhibitor modulates expression of PD-L1 on the cell surface - a potential mechanism of blocking interaction with PD-1
Weitsman, G.
Chan, J. Nuo En
Nedbal, J.
Barber, P. R.
Volgina, A.
Stevens, C.
Poland, S.
Ameer-Beg, S.
Suhling, K.
Rios-Doria, J.
Ng, T.
EUROPEAN JOURNAL OF CANCER, 2022, 174 : S70 - S70
[9] Expression of PD-L1 and PD-1 in conjunctival melanoma
Cao, Jinfeng
Richards, Kate
Jordanova, Ekaterina S.
Arinkovic, Marina
Hurkmans, Daan
van Duinen, Sjoerd G.
van der Velden, Pieter A.
Jager, Martine J.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2016, 57 (12)
[10] Small molecule inhibitors targeting the PD-1/PD-L1 signaling pathway
Wu, Qian
Jiang, Li
Li, Si-cheng
He, Qiao-jun
Yang, Bo
Cao, Ji
ACTA PHARMACOLOGICA SINICA, 2021, 42 (01) : 1 - 9

← 1 2 3 4 5 →