Life after death:: Controlling autoreactive CD8+ T-cell responses

被引：0
|
作者：
Braciale, TJ [1 ]
机构：
[1] Univ Virginia, Hlth Sci Ctr, Carter Immunol Ctr, Charlottesville, VA 22903 USA
[2] Univ Virginia, Hlth Sci Ctr, Dept Pathol, Charlottesville, VA USA
[3] Univ Virginia, Hlth Sci Ctr, Dept Microbiol, Charlottesville, VA USA
来源：
NATURE MEDICINE | 2001年 / 7卷 / 07期
关键词：
D O I：
10.1038/89886
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The uptake of apoptotic CD40L(+) cells by immature dendritic cells leads to dendritic-cell activation. This mechanism might account for the generation of autoreactive CD8(+) T cells in HIV infection and indicates a general mechanism for the regulation of autoimmune T-cell responses during infection.
引用
收藏
页码：774 / 775
页数：2
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