Utilizing the CF2H moiety as a H-bond-donating group in drug discovery

被引：71
|
作者：
Zafrani, Yossi [1 ]
Saphier, Sigal [1 ]
Gershonov, Eytan [1 ]
机构：
[1] Israel Inst Biol Res, Dept Organ Chem, IL-74100 Ness Ziona, Israel
来源：
FUTURE MEDICINAL CHEMISTRY | 2020年 / 12卷 / 05期
关键词：
bioisostere; difluoromethyl; drug design; hydrogen bond; POTENT INHIBITORS; DESIGN; FLUORINE;
D O I：
10.4155/fmc-2019-0309
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：361 / 366
页数：6
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