CAN mediated decarboxylative hydroxylation/alkoxylation of N-aryl-γ-lactam-carboxylic acids at room temperature:: an easy access to N-aryl-α-hydroxy/alkoxy-γ-lactams

被引：19

作者：

Haldar, Pranab ^{[1
]}

Ray, Jayanta K. ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Kharagpur 721302, W Bengal, India

来源：

TETRAHEDRON LETTERS | 2008年 / 49卷 / 22期

关键词：

decarboxylative hydroxylation; gamma-lactam-carboxylic acid; ceric ammonium nitrate; 1,5-dihydropyrrol-2-one;

D O I：

10.1016/j.tetlet.2008.03.147

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient and mild protocol for one-pot decarboxylative hydroxylation/alkoxylation of 1,3-diaryl-5-oxo-pyrrolidine-2-carboxylic acids to trans-5-hydroxy-1,4-diarylpyrrolidin-2-ones and 5-alkoxy-1,4-diaryl-1,5-dihydropyrrol-2-ones at room temperature using CAN in organo-aqueous solvent has been developed. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：3659 / 3662

页数：4