Dupilumab: An Opportunity to Unravel In Vivo Actions of IL-4 and IL-13 in Humans

被引：5
|
作者：
Roesner, Lennart M. [1 ]
Bridgewood, Charlie [2 ]
McGonagle, Dennis [2 ,3 ]
Wittmann, Miriam [2 ,3 ]
机构：
[1] Hannover Med Sch MHH, Dept Dermatol & Allergy, Div Immunodermatol & Allergy Res, Hannover, Germany
[2] Univ Leeds, Leeds Inst Rheumat & Musculoskeletal Med LIRMM, Leeds, W Yorkshire, England
[3] Leeds Teaching Hosp, Natl Inst Hlth Res NIHR, Leeds Biomed Res Ctr BRC, Leeds, W Yorkshire, England
来源：
JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2021年 / 141卷 / 08期
关键词：
D O I：
10.1016/j.jid.2021.02.007
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
The application of biologics in clinical practice allows immunological observations under real-life conditions. In a new article in the Journal of Investigative Dermatology, Bakker et al. (2021) use deep immune cell phenotyping to demonstrate how dupilumab acts in a targeted fashion on skin-homing T cells, the driver cells of atopic dermatitis.
引用
收藏
页码：1879 / 1881
页数：3
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