Genetic Studies in Autism

被引：5
|
作者：
Sudarshan, Shruthi [1 ]
Gupta, Neerja [1 ]
Kabra, Madhulika [1 ]
机构：
[1] All India Inst Med Sci, Dept Pediat, Div Genet, New Delhi 110029, India
来源：
INDIAN JOURNAL OF PEDIATRICS | 2016年 / 83卷 / 10期
关键词：
Autism; Autism spectrum disorders; Genetics; Copy number variations; Chromosomal microarray; Next generation sequencing; DE-NOVO MUTATIONS; SPECTRUM DISORDERS; SUSCEPTIBILITY; CHILDREN; NETWORK;
D O I：
10.1007/s12098-015-1989-7
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Autism is a complex neurodevelopmental disorder, which has captured the attention of not only pediatricians but also the parents. From the symptoms until the final diagnosis, parents undergo a diagnostic odyssey that involves a battery of tests without much yield. This has led to an increase in the referrals to the clinical geneticists to rule out the possible genetic etiology that can have implications for the parents for future pregnancy. This chapter focuses on the various genetic causes and their appropriate application in the evaluation of a child with Autism Spectrum Disorders (ASDs).
引用
收藏
页码：1133 / 1140
页数：8
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