The article is a response to publication of I.A. Mironenko and A.L. Zhuravlev "Biosocial problem in the context of global psychological science: about universal characteristics of a person". The article emphasizes methodological, theoretical and practical relevance of the problem raised in the article related to the search for answers to the challenges of globalization in Russian psychology. It is concluded that there are some obstacles to a constructive solution of the problem in Russian psychology at the present. The main one is that the mainstream of Russian psychology continues to rely on interpretation of mental as a process, while under new conditions a new ontological approach implying a change in interpretation of the subject of psychology is required. The author offers to understand the subject of psychology as person's inner world (see V.D. Shadrikov "The Inner world of a person"). It is argued that the concept of "ability" is the central category in subject's architectonics: the level structure of the latter allows a constructive approach to the consideration of biosocial problem in psychology. Another important point is the use of causal explanation in psychology: without changing in understanding of subject in psychology, the use of causal explanations is extremely limited, as it inevitably leads to a reduction of the mental to non -mental. This is evidenced by the almost complete disappearance of the term "explanation" in modern psychological research, which is widely used in Russian psychology. In fact, in these cases, the "explanation" is replaced by "interpretation" which refers to explanation that does not indicate a causal relationship between phenomena under study. Accepting person's inner world as the subject of psychology returns a cause -and -effect explanation to psychology, which in this case becomes non -reductive.