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Univ Milan, Fdn IRCCS CaGranda Osped Maggiore Policlin, Pediat Highly Intens Care Unit, Dept Pathophysiol & Transplantat, Via Commenda 9, I-20122 Milan, Italy Univ Milan, Fdn IRCCS CaGranda Osped Maggiore Policlin, Pediat Highly Intens Care Unit, Dept Pathophysiol & Transplantat, Via Commenda 9, I-20122 Milan, Italy