Sustained perinatal inflammatory syndrome of the extreme preterm infant. Important factor of morbidity and mortality in the extremely preterm infant. Part I: Basics of immunology

被引：0

作者：

Villalon, Hernan ^{[1
,2
]}

Caussade, Marie-Chantal ^{[1
]}

de los Angeles Vial, Maria ^{[3
]}

Pantoja, Stefanie ^{[1
]}

Vergara, Natalia ^{[1
]}

Jose Escobar, Juan ^{[2
]}

机构：

[1] Univ los Andes, Fac Med, Pediat, Santiago, Chile

[2] Clin Las Condes, Serv Neonatol, Santiago, Chile

[3] Cesfam Padre Damian Molokai, Valparaiso, Chile

来源：

REVISTA MEDICA CLINICA LAS CONDES | 2021年 / 32卷 / 06期

关键词：

Sustained Perinatal Inflammatory Syndrome; Extreme Preterm; Inflammation; Sequels; Immunological Basis; NF-KAPPA-B; MECHANISMS; ANTIOXIDANTS; DISEASES; NEWBORN; TERM;

D O I：

10.1016/j.rmclc.2021.10.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The inflammatory response associated with extreme preterm birth plays a relevant role in the prognosis of the newborn. The immaturity of the immune system fails to modulate the pro-inflammatory and anti-inflammatory mechanisms, triggering secondary damage with short, medium and long term sequelae. Objective: to review the immunological mechanisms involved in the sustained perinatal inflammatory syndrome, presenting possible prevention and treatment targets.

引用

页码：664 / 671

页数：8