Modeling of terfenadine adsorption onto MCM-41 mesoporous silica

被引:1
|
作者
Geszke-Moritz, Malgorzata [1 ]
Moritz, Michal [2 ]
机构
[1] Pomorski Uniwersytet Med Szczecinie, Biotechnol Med & Med Lab, Wydziale Farm, Zakladu Farmakognozji & Nat Srodkow Leczniczych, Szczecin, Poland
[2] Pomorski Uniwersytet Med Szczecinie, Biotechnol Med & Med Lab, Wydziale Farm, Zakladu Chem Farmaceutycznej, Szczecin, Poland
来源
PRZEMYSL CHEMICZNY | 2022年 / 101卷 / 07期
关键词
MCM-41; silica; drug adsorption; adsorption modeling; ISOTHERM; SURFACE; MCF;
D O I
10.15199/62.2022.7.4
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Terfenadine was adsorbed from its solns. in MeCN on MCM-41 mesoporous silica. Nonlinear fitting anal. was used to estimate the parameters of the Freundlich, Langmuir and Dubinin-Astakhov isotherm. MCM-41 silica was characterized by max. adsorption capacity of 220.7-229.3 mg/g (Dubinin-Astakhov model, various error function). Physisorption process was the main force of terfenadine adsorption onto MCM-41 mesoporous silica.
引用
收藏
页码:470 / 473
页数:4
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