A Toll-like receptor (TLR) 5 agonist entolimod mediates anti-metastatic activity via NK cell-dependent T cell activation

被引：0
|
作者：
Brackett, Craig [1 ]
Kojouharov, Bojidar [1 ]
Veith, Jean [1 ]
Greene, Kellee [1 ]
Gollnick, Sandra [1 ]
Burdelya, Lyudmila [1 ]
Abrams, Scott [1 ]
Gudkov, Andrei [1 ]
机构：
[1] Roswell Pk Canc Inst, Buffalo, NY 14263 USA
来源：
JOURNAL OF IMMUNOLOGY | 2015年 / 194卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
TUM2P.1029
引用
收藏
页数：2
相关论文
共 50 条
  • [1] The toll-like receptor 5 agonist entolimod suppresses hepatic metastases in a murine model of ocular melanoma via an NK cell-dependent mechanism
    Yang, Hua
    Brackett, Craig M.
    Morales-Tirado, Vanessa Marie
    Li, Zezhong
    Zhang, Qing
    Wilson, Matthew W.
    Benjamin, Camille
    Harris, Wayne
    Waller, Edmund K.
    Gudkov, Andrei V.
    Burdelya, Lyudmila G.
    Grossniklaus, Hans E.
    ONCOTARGET, 2016, 7 (03) : 2936 - 2950
  • [2] Toll-like receptor-5 agonist, entolimod, suppresses metastasis and induces immunity by stimulating an NK-dendritic-CD8+ T-cell axis
    Brackett, Craig M.
    Kojouharov, Bojidar
    Veith, Jean
    Greene, Kellee F.
    Burdelya, Lyudmila G.
    Gollnick, Sandra O.
    Abrams, Scott I.
    Gudkov, Andrei V.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (07) : E874 - E883
  • [3] Mast cell-dependent anorexia and hypothermia induced by mucosal activation of Toll-like receptor 7
    Hayashi, Tomoko
    Cottam, Howard B.
    Chan, Michael
    Jin, Guangyi
    Tawatao, Rommel I.
    Crain, Brian
    Ronacher, Lisa
    Messer, Karen
    Carson, Dennis A.
    Corr, Maripat
    AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2008, 295 (01) : R123 - R132
  • [4] A Toll-like Receptor 5 agonist entolimod mitigates radiation damage through a neutrophil-dependent mechanism
    Brackett, Craig M.
    Greene, Kellee
    Kandar, Bojidar
    Trageser, Nicholas
    Kandefer, Rachel
    Pal, Srabani
    Burdelya, Lyudmila
    Gudkov, Andrei
    JOURNAL OF IMMUNOLOGY, 2019, 202 (01):
  • [5] Critical role of Toll-like receptor signaling in NK cell activation
    Guo Qie
    Zhang Cai
    CHINESE SCIENCE BULLETIN, 2012, 57 (24): : 3192 - 3202
  • [6] Critical role of Toll-like receptor signaling in NK cell activation
    GUO Qie & ZHANG Cai Institute of Immunopharmacology & Immunotherapy
    Science Bulletin, 2012, (24) : 3192 - 3202
  • [7] A phase I study of the toll-like receptor 5 (TLR5) agonist, entolimod in patients (pts) with advanced cancers.
    Bakhribah, Hatoon
    Dy, Grace K.
    Ma, Wen Wee
    Zhao, Yujie
    Opyrchal, Mateusz
    Purmal, Andrei
    Gollnick, Sandra
    Brady, William E.
    Fetterly, Gerald J.
    Ngamphaiboon, Nuttapong
    Reungwetwattana, Thanyanan
    Jacob, Sandra M.
    O'Hara, Corrie
    Siedlecki, Francine
    Adjei, Araba
    Burdelya, Lyudmila
    Bespalov, Ivan
    Miller, Langdon L.
    Gudkov, Andrei
    Adjei, Alex A.
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
  • [8] Natural Killer Cell-Dependent Anti-Fibrotic Pathway in Liver Injury via Toll-Like Receptor-9
    Abu-Tair, Lina
    Axelrod, Jonathan H.
    Doron, Sarit
    Ovadya, Yossi
    Krizhanovsky, Valery
    Galun, Eithan
    Amer, Johnny
    Safadi, Rifaat
    PLOS ONE, 2013, 8 (12):
  • [9] T Cell-dependent Anti-tumor Activity of NK Cells
    Shanker, Anil
    Uzhachenko, Roman V.
    JOURNAL OF IMMUNOTHERAPY, 2012, 35 (09) : 759 - 759
  • [10] Cooperation between T cell receptor and Toll-like receptor 5 signaling for CD4+ T cell activation
    Rodriguez-Jorge, Otoniel
    Kempis-Calanis, Linda A.
    Abou-Jaoude, Wassim
    Gutiérrez-Reyna, Darely Y.
    Hernandez, Celine
    Ramirez-Pliego, Oscar
    Thomas-Chollier, Morgane
    Spicuglia, Salvatore
    Santana, Maria A.
    Thieffry, Denis
    SCIENCE SIGNALING, 2019, 12 (577)
12345