Transport through liquid membranes containing omeprazole and lansoprazole

被引:0
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作者
Nagappa, AN [1 ]
Pandi, PV
Girish, RK
Shanmukh, I
机构
[1] Birla Inst Technol & Sci, Pharm Grp, Pilani 333031, Rajasthan, India
[2] SCS Coll Pharm, Dept Pharmacol, Harapanahalli 583131, Karnataka, India
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中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Oseprazoe and lansoprazole, the therapeutically important drugs belonging to proton pump inhibitor category are extensively used in the treatment of gastric ulcers. Transport through liquid membranes generated by these drugs in lecithin-cholesterol mixture in series with a supporting membrane has been studied. The data obtained show tire formation of liquid membrane in series with tie supporting membrane, Transport of canons, chloride and bicarbonate ions in the presence liquid membranes generated by omeprazole and lanzoprazole indicate the modification in the permeability of various permeants.
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页码:406 / 409
页数:4
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