Functional Mitral Regurgitation in Heart Failure

被引：7
|
作者：
Shah, Tara [1 ]
Zhong, Ming [1 ]
Minutello, Robert M. [1 ]
机构：
[1] New York Presbyterian Hosp, Weill Cornell Med Coll, Div Cardiol, New York, NY USA
来源：
CARDIOLOGY IN REVIEW | 2019年 / 27卷 / 06期
关键词：
functional mitral regurgitation; heart failure; transcatheter valve; annuloplasty; CARDIAC RESYNCHRONIZATION THERAPY; LEFT-VENTRICULAR FUNCTION; VALVE REPAIR; QUANTITATIVE ASSESSMENT; DILATED CARDIOMYOPATHY; MYOCARDIAL-INFARCTION; PERCUTANEOUS REPAIR; RISK PATIENTS; ANNULOPLASTY; MECHANISM;
D O I：
10.1097/CRD.0000000000000269
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Functional mitral regurgitation (FMR) in the setting of left ventricular (LV) dysfunction and heart failure portends a poor prognosis. Guideline-directed medical therapy remains the cornerstone of initial treatment, with emphasis placed on treatment of the underlying LV dysfunction, as FMR is a secondary phenomenon and a disease due to LV remodeling. Surgical correction of FMR is controversial because it typically does not address the underlying mechanism and etiology of the condition. However, new, minimally invasive transcatheter therapies, in particular the MitraClip system, have shown promise in the treatment of FMR in selected patients. This review will summarize the pathophysiology underlying FMR, the prognosis of patients with heart failure and FMR, and the various medical and procedural treatment options currently available and under investigation.
引用
收藏
页码：327 / 336
页数：10
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