GC-MS analysis and anti-microbial activity of Prunella vulgaris L. extracts

被引：6

作者：

Ozbek, Oguz ^{[1
]}

Saglam, Burak ^{[2
]}

Usta, Necibe Canan ^{[3
]}

Budak, Yakup ^{[2
]}

机构：

[1] Zonguldak Bulent Ecevit Univ, Sci & Technol Applicat & Res Ctr, TR-67600 Zonguldak, Turkey

[2] Tokat Gaziosmanpasa Univ, Fac Arts & Sci, Dept Chem, TR-60250 Tokat, Turkey

[3] Tokat Gaziosmanpasa Univ, Fac Arts & Sci, Dept Biol, TR-60250 Tokat, Turkey

来源：

JOURNAL OF THE INDIAN CHEMICAL SOCIETY | 2022年 / 99卷 / 06期

关键词：

Prunella vulgaris L; Anti-microbial activity; GC-MS; Pathogen; INHIBITION; CULTURES; CANCER;

D O I：

10.1016/j.jics.2022.100460

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this study, the chemical composition of the methanol, hexane and ethyl acetate extracts of Prunella vulgaris L. were investigated by gas chromatography-mass spectrometry (GC-MS) method. 2-hydroxy-5-methylbenzaldehyde (15.70%), linolenic acid (45.50%) and icosane (16.24%) were found to be the most abundant in methanol, hexane and ethyl acetate extracts, respectively. Following the determination of chemical components of the Prunella vulgaris L. extracts, their anti-microbial activities against certain human pathogenic bacteria were tested and minimal inhibitory concentrations (MIC) were determined. While some extracts of Prunella vulgaris L. show anti-microbial activity well above the standards (penicillin and tetracycline), it was determined that in general all the extracts showed good anti-microbial activity against these pathogenic bacteria.

引用

页数：5

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