Dearomative (3+2) cycloaddition of 2-substituted 3,5-dinitropyridines and N-methyl azomethine ylide

被引：10

作者：

Bastrakov, Maxim A. ^{[1
]}

Fedorenko, Alexey K. ^{[1
]}

Starosotnikov, Alexey M. ^{[1
]}

Kachala, Vadim V. ^{[1
]}

Shevelev, Svyatoslav A. ^{[1
]}

机构：

[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, 47 Leninsky Ave, Moscow 119991, Russia

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2019年 / 55卷 / 01期

基金：

俄罗斯基础研究基金会;

关键词：

azomethine ylide; pyridine; pyrrolidine; dearomatization; 1; 3-dipolar cycloaddition; 1,3-DIPOLAR CYCLOADDITION; STRATEGIES;

D O I：

10.1007/s10593-019-02421-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,3-Dipolar cycloaddition of various 2-substituted 3,5-dinitropyridines and unstabilized N-methyl azomethine ylide has been studied. It was found that, depending on the nature of the substituent, the reaction results in addition of one or two equivalents of 1,3-dipole to the pyridine ring. Eventually, a convenient method for the synthesis of differently substituted heterocyclic systems containing one or two pyrrolidine fragments fused with a pyridine ring has been demonstrated.

引用

页码：72 / 77

页数：6

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