We investigate the non-perturbative equivalence of some heterotic/type II dual pairs with N = 2 supersymmetry. The perturbative heterotic scalar manifolds are respectively SU(1, 1)/U(1) x SO(2, 2 + N-V)/SO(2) x SO(2 + N-V) and SO(4, 4 + N-H)/SO(4) x SO(4 + N-H) for moduli in the vector multiplets and hypermultiplets. The models under consideration correspond, on the type II side, to self-mirror Calabi-Yau threefolds with Hedge numbers h(1,1) = N-V + 3 = h(2,1) = N-H + 3, which are K3 fibrations. We consider three classes of dual pairs, with N-V = N-H = 8, 4 and 2. The models with h(1,1) = 7 and 5 provide new constructions, while the h(1,1) = 11, already studied in the literature, is reconsidered here. Perturbative R-2-like corrections are computed on the heterotic side by using a universal operator whose amplitude has no singularities in the (T, U) space, and can therefore be compared with the type II side result. We point out several properties connecting K3 fibrations and spontaneous breaking of the N = 4 supersymmetry to N = 2. As a consequence of the reduced S- and T- duality symmetries, the instanton numbers in these three classes are restricted to integers, which are multiples of 2, 2 and 4, for N-V = 8, 4 and 2, respectively. (C) 1999 Elsevier Science B.V.