What's Next for Acute Heart Failure Research?

被引：10
|
作者：
Collins, Sean P. [1 ]
Levy, Phillip D. [3 ]
Fermann, Gregory J. [4 ]
Givertz, Michael M. [5 ]
Martindale, Jennifer M. [6 ]
Pang, Peter S. [7 ,8 ]
Storrow, Alan B. [1 ]
Diercks, Deborah D. [9 ]
Felker, G. Michael [10 ]
Fonarow, Gregg C. [11 ]
Lanfear, David J. [12 ]
Lenihan, Daniel J. [2 ]
Lindenfeld, JoAnn M. [2 ]
Peacock, W. Frank [13 ]
Sawyer, Douglas M. [14 ]
Teerlink, John R. [15 ,16 ]
Butler, Javed [17 ]
机构：
[1] Vanderbilt Univ, Med Ctr, Dept Emergency Med, Nashville, TN 37235 USA
[2] Vanderbilt Univ, Med Ctr, Div Cardiol, Nashville, TN USA
[3] Wayne State Univ, Dept Emergency Med, Detroit, MI USA
[4] Univ Cincinnati, Med Ctr, Dept Emergency Med, Cincinnati, OH 45267 USA
[5] Brigham & Womens Med Ctr, Div Cardiol, Boston, MA USA
[6] Suny Downstate Med Ctr, Dept Emergency Med, Brooklyn, NY 11203 USA
[7] Indiana Univ, Sch Med, Dept Emergency Med, Indianapolis, IN USA
[8] Indianapolis EMS, Indianapolis, IN USA
[9] Univ Texas Southwestern Med Ctr Dallas, Dept Emergency Med, Dallas, TX 75390 USA
[10] Duke Univ, Med Ctr, Div Cardiol 8, Durham, NC USA
[11] Univ Calif Los Angeles, Div Cardiol, Ronald Reagan Med Ctr, Los Angeles, CA USA
[12] Henry Ford Hosp, Div Cardiol, Detroit, MI 48202 USA
[13] Baylor Univ, Dept Emergency Med, Med Ctr, Houston, TX 77030 USA
[14] Maine Med Ctr, Div Cardiol, Portland, ME 04102 USA
[15] San Francisco VA Med Ctr, Sect Cardiol, San Francisco, CA USA
[16] Univ Calif San Francisco, San Francisco, CA 94143 USA
[17] SUNY Stony Brook, Div Cardiol, Med Ctr, Stony Brook, NY 11794 USA
来源：
ACADEMIC EMERGENCY MEDICINE | 2018年 / 25卷 / 01期
关键词：
EMERGENCY-DEPARTMENT; CARE; MODEL;
D O I：
10.1111/acem.13331
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Each year over one million patients with acute heart failure (AHF) present to a United States emergency department (ED). The vast majority are hospitalized for further management. The length of stay and high postdischarge event rate in this cohort have changed little over the past decade. Therapeutic trials have failed to yield substantive improvement in postdischarge outcomes; subsequently, AHF care has changed little in the past 40 years. Prior research studies have been fragmented as either " inpatient" or " ED-based." Recognizing the challenges in identification and enrollment of ED patients with AHF, and the lack of robust evidence to guide management, an AHF clinical trials network was developed. This network has demonstrated, through organized collaboration between cardiology and emergency medicine, that many of the hurdles in AHF research can be overcome. The development of a network that supports the collaboration of acute care and HF researchers, combined with the availability of federally funded infrastructure, will facilitate more efficient conduct of both explanatory and pragmatic trials in AHF. Yet many important questions remain, and in this document our group of emergency medicine and cardiology investigators have identified four high-priority research areas.
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页码：85 / 93
页数：9
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