SYNTHESIS, ANTIMICROBIAL AND ANTIMALARIAL ACTIVITIES OF SOME CARBAZOLE DERIVATIVES

被引：0
|
作者：
Kadnor, Vijay A. [1 ]
Shirole, Gopinath D. [2 ]
Mhaske, Ganesh R. [2 ]
Shelke, Sharad N. [2 ]
机构：
[1] ACS Coll Satral, Dept Chem, Ahmednagar, Maharashtra, India
[2] SSGM Coll, Dept Chem, Ahmednagar, Maharashtra, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2017年 / 27卷 / 01期
关键词：
9-Ethyl-9H-carbazole-3-carbaldehyde; Pyrazolines; Chromones; Antimicrobial; Antimalarial; BIOLOGICAL EVALUATION; ANTITUMOR; DESIGN;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of novel carbazole-tethered pyrazolines and chromone derivatives was synthesized from 9-ethyl-9H-carbazole-3-carbaldehyde. The structures of newly synthesized compounds were confirmed by their infrared, nuclear magnetic resonance and mass spectral data. All the synthesized compounds were screened for their in vitro antibacterial, antifungal, and antimalarial activity. Some of the synthesized compounds showed comparable or even better antibacterial, antifungal, and antimalarial activities than the reference drugs ampicillin, griseofulvin, and quinine, respectively. [GRAPHICS] .
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页码：59 / 64
页数：6
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