Synthesis and characteristics of Fe-filled multi-walled carbon nanotubes for biomedical application

被引：29
|
作者：
Moench, I. [1 ]
Leonhardt, A. [1 ]
Meye, A. [2 ]
Hampel, S. [1 ]
Kozhuharova-Koseva, R. [1 ]
Elefant, D. [1 ]
Wirth, M. P. [2 ]
Buechner, B.
机构：
[1] IFW Dresden, Leibniz Inst Solid State & Mat Res Dresden, Helmholtzstr 20, D-01069 Dresden, Germany
[2] Tech Univ Dresden, Dept Urol, D-01062 Dresden, Germany
来源：
PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON NANOSCIENCE AND TECHNOLOGY | 2007年 / 61卷
关键词：
D O I：
10.1088/1742-6596/61/1/164
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Multifunctional nanocontainers can be produced based on partially filled Fe-multi walled carbon nanotubes (MWCNTs). Using thermal decomposition ferrocene filled nanotubes can be grown aligned on substrates. The encapsulated metal nanowires have diameters of 5-30nm and a length up to few microns. They consist of single-crystalline of alpha- and gamma-Fe-phases. Using heat treatment, it is possible to transform gamma-Fe into alpha-Fe. With the aid of wet chemical methods the nanotubes can be opened and additionally filled with an agent, e. g., therapeutic agents (carboplatin) or other metals (copper). Initial studies do not show a high toxicity over a period of 440 days. These materials can be used for drug delivery and hyperthermia. The specific absorption rate (SAR) is greater than 100W/(g-alpha-Fe) in a magnetic field of 18kA/m (f = 250kHz).
引用
收藏
页码：820 / 824
页数：5
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