Predominance of Candida tropicalis bloodstream infections in a Singapore teaching hospital

被引：21
|
作者：
Chai, Yi Ann Louis
Wang, Yue
Khoo, Ai Leng
Chan, Fong Yee
Chow, Carol
Kumarasinghe, Gamini
Singh, Kamaljit
Tambyah, Paul Ananth
机构：
[1] Natl Univ Singapore Hosp, Dept Med, Singapore 117548, Singapore
[2] Inst Mol & Cell Biol, Microbial Collect & Screening Lab, Singapore, Singapore
[3] Natl Univ Singapore Hosp, Dept Pharm, Singapore 117548, Singapore
[4] Natl Univ Singapore Hosp, Dept Lab Med, Singapore 117548, Singapore
[5] Rush Univ, Med Ctr, Chicago, IL 60612 USA
[6] Natl Univ Singapore, Fac Med, Singapore 117548, Singapore
来源：
MEDICAL MYCOLOGY | 2007年 / 45卷 / 05期
关键词：
Candida tropicalis; Singapore; epidemiology;
D O I：
10.1080/13693780701385868
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
An 18- month epidemiologic investigation of Candida bloodstream infections in a Singapore hospital identified 52 candidemic patients: 36% of whose infections were caused by C. tropicalis, 29% were due to C. albicans, 10% with C. parapsilosis and 21% involved C. glabrata. A predominant clonal C. tropicalis strain was demonstrated. No association with ICU stay, prior exposure to fluconazole/ broad- spectrum antibiotics or increased mortality was found in this apparent shift towards non- albicans Candida species as the primary agents of candidemia.
引用
收藏
页码：435 / 439
页数：5
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