In this issue of Developmental Cell, Skopelitis et al. (2017) demonstrate that sharp boundaries of gene expression can be created by threshold-based readout of mobile small RNA gradients. Support for this hypothesis comes from manipulation of small RNAs involved in top-bottom leaf patterning and from a novel synthetic biology approach.
机构:
Univ Miguel Hernandez, Div Genet, Alicante 03202, Spain
Univ Miguel Hernandez, Inst Bioingn, Alicante 03202, SpainUniv Miguel Hernandez, Div Genet, Alicante 03202, Spain