How to Manage Withdrawal of Sedation and Analgesia in Mechanically Ventilated COVID-19 Patients?

被引：8

作者：

Ego, Amedee ^{[1
]}

Halenarova, Katarina ^{[1
]}

Creteur, Jacques ^{[1
]}

Taccone, Fabio Silvio ^{[1
]}

机构：

[1] Univ Libre Bruxelles ULB, Erasme Hosp, Dept Intens Care, B-1070 Brussels, Belgium

来源：

JOURNAL OF CLINICAL MEDICINE | 2021年 / 10卷 / 21期

关键词：

sedation; analgesia; COVID-19; withdrawal; management; KETAMINE;

D O I：

10.3390/jcm10214917

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

COVID-19 patients suffering from severe acute respiratory distress syndrome (ARDS) require mechanical ventilation (MV) for respiratory failure. To achieve these ventilatory goals, it has been observed that COVID-19 patients in particular require high regimens and prolonged use of sedatives, analgesics and neuromuscular blocking agents (NMBA). Withdrawal from analgo-sedation may induce a "drug withdrawal syndrome " (DWS), i.e., clinical symptoms of anxiety, tremor, agitation, hallucinations and vomiting, as a result of adrenergic activation and hyperalgesia. We describe the epidemiology, mechanisms leading to this syndrome and our strategies to prevent and treat it.

引用

页数：8

共 50 条

[1] Analgesia and Sedation Strategies in Mechanically Ventilated Adults with COVID-19
Adams, Christopher D.
Altshuler, Jerry
Barlow, Brooke L.
Dixit, Deepali
Droege, Christopher A.
Effendi, Muhammad K.
Heavner, Mojdeh S.
Johnston, Jackie P.
Kiskaddon, Amy L.
Lemieux, Diana G.
Lemieux, Steven M.
Littlefield, Audrey J.
Owusu, Kent A.
Rouse, Ginger E.
Thompson Bastin, Melissa L.
Berger, Karen
[J]. PHARMACOTHERAPY, 2020, 40 (12): : 1180 - 1191
[2] Sedation in mechanically ventilated patients with COVID-19
Page, Valerie
[J]. LANCET RESPIRATORY MEDICINE, 2021, 9 (03): : 218 - 219
[3] Effects of Analgesia and Sedation Dosing on Mortality in Mechanically Ventilated COVID-19 Patients
Choi, J.
Shende, T.
Engracia, D.
Lo, A.
Huerta, L.
[J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2022, 205
[4] STANDARD SEDATION AND SEDATION WITH ISOFLURANE IN MECHANICALLY VENTILATED PATIENTS WITH COVID-19
Hanidziar, Dusan
Baldyga, Kathryn
Ji, Christine
Lu, Jing
Zheng, Hui
Wiener-Kronish, Jeanine
Xie, Zhongcong
[J]. CRITICAL CARE MEDICINE, 2021, 49 (01) : 112 - 112
[5] The Use of Analgesia and Sedation in Mechanically Ventilated Patients With COVID-19 Acute Respiratory Distress Syndrome
Kapp, Christopher M.
Zaeh, Sandra
Niedermeyer, Shannon
Punjabi, Naresh M.
Siddharthan, Trishul
Damarla, Mahendra
[J]. ANESTHESIA AND ANALGESIA, 2020, 131 (04): : E198 - E200
[6] SEDATION AND PARALYSIS REQUIREMENTS IN MECHANICALLY VENTILATED PATIENTS WITH COVID-19
Kolar, Rachel
Popa, Andreea
Matta, Maroun
Hejal, Rana
Traeger, Jessica
Giddings, Olivia Kathryn
[J]. CRITICAL CARE MEDICINE, 2022, 50 (01) : 145 - 145
[7] The Use of Analgesia and Sedation in Mechanically Ventilated Patients With COVID-19 Acute Respiratory Distress Syndrome Response
Hanidziar, Dusan
Bittner, Edward A.
[J]. ANESTHESIA AND ANALGESIA, 2020, 131 (04): : E200 - E202
[8] Sedation, narcotic and neuromuscular blockade in mechanically ventilated patients with COVID-19
Rizvi, Ghazi
Yamane, David
Davison, Danielle
Williams, Jeffrey
Heinz, Eric R.
[J]. TRENDS IN ANAESTHESIA AND CRITICAL CARE, 2021, 39 : 19 - 20
[9] Sedation of Mechanically Ventilated COVID-19 Patients: Challenges and Special Considerations
Hanidziar, Dusan
Bittner, Edward A.
[J]. ANESTHESIA AND ANALGESIA, 2020, 131 (01): : E40 - E41
[10] SEDATION REQUIREMENTS AND PRACTICES FOR MECHANICALLY VENTILATED CRITICALLY ILL COVID-19 PATIENTS
Balakrishna, Aditi
Walsh, Elisa
Hamidi, Arzo
Berg, Sheri
Austin, Daniel
Pino, Richard
Hanidziar, Dusan
Chang, Marvin
Bittner, Edward
[J]. CRITICAL CARE MEDICINE, 2021, 49 (01) : 91 - 91

← 1 2 3 4 5 →