PATHOPHYSIOLOGY OF INCREASED FETAL NUCHAL TRANSLUCENCY THICKNESS

被引:13
|
作者
Chen, Chih-Ping [1 ,2 ,3 ,4 ,5 ,6 ]
机构
[1] Mackay Mem Hosp, Dept Obstet & Gynecol, Taipei, Taiwan
[2] Mackay Mem Hosp, Dept Med Res, Taipei, Taiwan
[3] Asia Univ, Dept Biotechnol, Taichung, Taiwan
[4] China Med Univ, Coll Chinese Med, Sch Chinese Med, Taichung, Taiwan
[5] Natl Yang Ming Univ, Inst Clin & Community Hlth Nursing, Taipei 112, Taiwan
[6] Natl Yang Ming Univ, Dept Obstet & Gynecol, Taipei 112, Taiwan
来源
关键词
fetus; nuchal translucency; pathophysiology; NEURAL CREST CELLS; CHROMOSOMALLY ABNORMAL FETUSES; MAJOR CARDIAC DEFECTS; TRISOMY; 16; MOUSE; COLLAGEN TYPE-VI; CYSTIC HYGROMA; NORMAL KARYOTYPE; 1ST-TRIMESTER ULTRASOUND; LYMPHEDEMA-DISTICHIASIS; EXTRACELLULAR-MATRIX;
D O I
10.1016/S1028-4559(10)60029-0
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Increased fetal nuchal translucency thickness is associated with trisomy 13, trisomy 18, trisomy 21, Turner syndrome, other sex chromosome abnormalities, as well as many fetal anomalies and genetic syndromes This article provides a comprehensive review of the cardinal proposed pathophysiology including altered composition of the extracellular matrix, abnormalities of the heart and great arteries, and disturbed or delayed lymphatic development [Taiwan J Obstet Gynecol 2010,49(2) 133-138]
引用
收藏
页码:133 / 138
页数:6
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