Noninvasive point-of-care 13C-Methacetin Breath Test (MBT) predicts risk of clinical deterioration independently of currently used prognostic indicators in patients with decompensated NASH cirrhosis

被引：0
|
作者：
Vierling, John [1 ,2 ]
Sanyal, Arun [3 ]
Friedman, Scott [4 ]
Shiffman, Mitchell [5 ]
Chan, Jean [6 ]
Werner, Raphael [7 ]
Bosch, Jaime [8 ,9 ]
机构：
[1] Baylor Coll Med, Sect Gastroenterol & Hepatol, Houston, TX 77030 USA
[2] Baylor Coll Med, Div Abdominal Transplantat, Houston, TX 77030 USA
[3] Virginia Commonwealth Univ, Med Ctr, Div Gastroenterol, Richmond, VA USA
[4] Icahn Sch Med Mt Sinai, Div Liver Dis, New York, NY 10029 USA
[5] Bon Secours Liver Inst Virginia, Richmond, VA USA
[6] Conatus Pharmaceut Inc, San Diego, CA USA
[7] Exalenz Biosci, Modiin, Israel
[8] Hosp Clin Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain
[9] Univ Spital, Inselspital, Bern, Switzerland
来源：
JOURNAL OF HEPATOLOGY | 2020年 / 73卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
LBP28
引用
收藏
页码：S139 / S140
页数：2
相关论文
共 14 条
  • [1] NONINVASIVE POINT-OF-CARE 13C-METHACETIN BREATH TEST (MBT) PREDICTS RISK OF CLINICAL DECOMPENSATION EVENTS IN PATIENTS WITH NON-ALCOHOLIC STEATOHEPATITIS (NASH) CIRRHOSIS AND SEVERE PORTAL HYPERTENSION (SPH)
    Guggenheim, Gil
    Garcia-Tsao, Guadalupe
    Bosch, Jaime
    Chan, Jean Lin
    Werner, Raffi
    Sanyal, Arun J.
    HEPATOLOGY, 2019, 70 : 1047A - 1048A
  • [2] The non-invasive 13C-Methacetin Breath Test (MBT) predicts survival and complications of patients with cirrhosis: Interim analysis of a multicenter clinical trial
    Stravitz, Richard
    Mizrahi, Meir
    Lalazar, Gadi
    Guggenheim, Gil D.
    Hershkowitz, Avraham D.
    Ben Oren, Ilan
    Reuben, Adrian
    Brown, Kimberly Ann
    Gordon, Stuart C.
    Ilan, Yaron
    Sanyal, Arun J.
    HEPATOLOGY, 2012, 56 : 922A - 922A
  • [3] 13C-Methacetin Breath Test accurately assesses clinically significant portal hypertension in patients with NASH cirrhosis
    Ilan, Y.
    Harrison, S. A.
    Traber, P. G.
    Chalasani, N. P.
    Garcia-Tsao, G.
    JOURNAL OF HEPATOLOGY, 2017, 66 (01) : S100 - S100
  • [4] The utility of the 13C-methacetin breath test in predicting the long-term survival of patients with decompensated cirrhosis
    Moran, Segundo
    Mina, Aline
    Duque, Ximena
    Ortiz-Olvera, Nayeli
    Rodriguez-Leal, Gustavo
    Alfredo Sierra-Ramirez, Jose
    Medina-Santillan, Roberto
    Mera, Robertino M.
    Uribe, Misael
    JOURNAL OF BREATH RESEARCH, 2017, 11 (03)
  • [5] 13C-methacetin breath test is a highly accurate non-invasive point of care test for detecting CSPH in patients with NASH
    Bosch, J.
    Bureau, C.
    Chalasani, N.
    Lawitz, E.
    Abdelmalek, M.
    Rinella, M.
    Harrison, S.
    Berzigotti, A.
    Sanyal, A.
    Noureddin, M.
    Rockey, D.
    Ber, T. I.
    Ilan, Y.
    Garcia-Tsao, G.
    JOURNAL OF HEPATOLOGY, 2018, 68 : S115 - S115
  • [6] Point-of-care continuous 13C-methacetin breath test improves decision making in acute liver disease: Results of a pilot clinical trial
    Lalazar, Gadi
    Adar, Tomer
    Ilan, Yaron
    WORLD JOURNAL OF GASTROENTEROLOGY, 2009, 15 (08) : 966 - 972
  • [7] Point-of-care continuous 13C-methacetin breath test improves decision making in acute liver disease: Results of a pilot clinical trial
    Gadi Lalazar
    Tomer Adar
    Yaron Ilan
    World Journal of Gastroenterology, 2009, 15 (08) : 966 - 972
  • [8] 13C-METHACETIN BREATH TEST CORRELATES WITH CLINICAL INDICES OF LIVER DISEASE SEVERITY IN PATIENTS WITH PRIMARY BILIARY CIRRHOSIS
    Kochel-Jankowska, A.
    Hartleb, M.
    Jonderko, K.
    Kaminska, M.
    Kasicka-Jonderko, A.
    JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2013, 64 (01): : 27 - 33
  • [9] The point of care 13C-Methacetin Breath Test predicts risk of long-term liver-related death or transplantation in patients with chronic liver disease: a sensitive, noninvasive monitoring tool in clinical hepatology
    Shiffman, M. L.
    Siddiqui, M. S.
    Khoury, T.
    Gordon, S. C.
    Lalazar, G.
    Reuben, A.
    McCullough, A. J.
    Reddy, K. R.
    Poordad, F.
    Younossi, Z. M.
    Vierling, J. M.
    Fich, A.
    Zuckerman, E.
    Ilan, Y.
    Sanyal, A. J.
    JOURNAL OF HEPATOLOGY, 2017, 66 (01) : S668 - S669
  • [10] USE OF 13C-METHACETIN BREATH TEST (MBT) TO PREDICT CIRRHOSIS COMPLICATIONS AND MORTALITY IN PATIENTS WITH LOW MELD SCORES EVALUATED OR LISTED FOR LIVER TRANSPLANTATION (LT)
    Stravitz, R. T.
    Reuben, A.
    Mizrahi, M.
    Lalazar, G.
    Guggenheim, G.
    Hershkowitz, A.
    Ben Oren, I.
    Hemed, N.
    Brown, K.
    Gordon, S.
    Ilan, Y.
    Sanyal, A.
    JOURNAL OF HEPATOLOGY, 2014, 60 (01) : S240 - S240
12