Relationship between duration of untreated psychosis and neurocognition and social cognition in first-episode psychosis

被引：10
|
作者：
On, Zhi Xiang [1 ]
Cotton, Susan [2 ,3 ]
Farhall, John [1 ]
Killackey, Eoin [2 ,3 ]
Allott, Kelly [2 ,3 ]
机构：
[1] La Trobe Univ, Dept Psychol & Counselling, Bundoora, Vic 3086, Australia
[2] Orygen, Natl Ctr Excellence Youth Mental Hlth, 35 Poplar Rd, Parkville, Vic 3029, Australia
[3] Univ Melbourne, Ctr Youth Mental Hlth, Melbourne, Vic 3010, Australia
来源：
SCHIZOPHRENIA RESEARCH | 2016年 / 176卷 / 2-3期
基金：
英国医学研究理事会; 澳大利亚研究理事会;
关键词：
Duration of untreated psychosis (DUP); Neurocognition; Social cognition; First-episode psychosis (FEP); Neurotoxicity hypothesis; SCHIZOPHRENIA; INTERVENTION;
D O I：
10.1016/j.schres.2016.06.018
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Cognitive impairment is common in first-episode psychosis (FEP); however, the relationship between duration of untreated psychosis (DUP) and neurocognition remains controversial, and no studies have examined the relationship between DUP and social cognition. This study involved secondary data analysis of baseline data from a randomised controlled trial of supported employment; 122 out 146 young people with FEP met inclusion criteria for this study. Results showed that DUP was not associated with neurocognitive or social cognitive performance. Results do not provide support for the neurotoxicity hypothesis of psychosis. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码：529 / 532
页数：4
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