Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC)-Associated Renal Cancer: A Comparison of Fumarate Hydratase (FH) and S-(2-Succino)-Cysteine (2SC) Immunohistochemistry as Ancillary Tools

被引:0
|
作者
Chen, Ying-Bei
Kong, Max
Bialik, Ann
Mehra, Rohit
Alva, Ajjai
Frizzell, Norma
Sirintrapun, Sahussapont
Gopalan, Anuradha
Al-Ahmadie, Hikmat
Fine, Samson
Chinnaiyan, Arul
Tickoo, Satish
Reuter, Victor
机构
[1] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA
[2] Univ Michigan, Ann Arbor, MI 48109 USA
[3] Univ S Carolina, Columbia, SC 29208 USA
关键词
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
838
引用
收藏
页码:211A / 211A
页数:1
相关论文
共 32 条
  • [1] Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC)-Associated Renal Cancer: A Comparison of Fumarate Hydratase (FH) and S-(2-Succino)-Cysteine (2SC) Immunohistochemistry as Ancillary Tools
    Chen, Ying-Bei
    Kong, Max
    Bialik, Ann
    Mehra, Rohit
    Alva, Ajjai
    Frizzell, Norma
    Sirintrapun, Sahussapont
    Gopalan, Anuradha
    Al-Ahmadie, Hikmat
    Fine, Samson
    Chinnaiyan, Arul
    Tickoo, Satish
    Reuter, Victor
    MODERN PATHOLOGY, 2015, 28 : 211A - 211A
  • [2] A comparison of S-(2-succino) Cysteine (2SC) and Fumarate Hydratase (FH) Immunohistochemistry for Screening of Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC) Syndrome in Uterine Smooth Muscle Tumors
    Monsrud, Ashley
    McHenry, Austin
    Pors, Jennifer
    Folkins, Ann
    Hodan, Rachel
    Longacre, Teri
    LABORATORY INVESTIGATION, 2024, 104 (03) : S1213 - S1214
  • [3] Age as a Surveillance Factor for Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC) Syndrome Screening in Uterine Leiomyomas with Fumarate Hydratase (FH) And S(2-Succino) Cysteine (2SC) Immunohistochemistry
    McHenry, Austin
    Monsrud, Ashley
    Pors, Jennifer
    Hodan, Rachel
    Folkins, Ann
    Longacre, Teri
    LABORATORY INVESTIGATION, 2024, 104 (03) : S1207 - S1208
  • [4] Characterization of protein S-(2-succino)-cysteine (2SC) succination as a biomarker for fumarate hydratase-deficient renal cell carcinoma
    Mannan, Rahul
    Wang, Xiaoming
    Bawa, Pushpinder S.
    Chugh, Seema
    Chinnaiyan, Anya K.
    Rangaswamy, Roshni
    Zhang, Yuping
    Cao, Xuhong
    Smith, Steven C.
    Trpkov, Kiril
    Williamson, Sean R.
    Sangoi, Ankur R.
    Mohanty, Sambit
    McKenney, Jesse K.
    Gupta, Sounak
    Magi-Galluzzi, Cristina
    Argani, Pedram
    Osunkoya, Adeboye O.
    Chinnaiyan, Arul M.
    Dhanasekaran, Saravana M.
    Mehra, Rohit
    HUMAN PATHOLOGY, 2023, 134 : 102 - 113
  • [5] Pattern multiplicity and fumarate hydratase (FH)/S-(2-succino)-cysteine (2SC) staining but not eosinophilic nucleoli with perinucleolar halos differentiate hereditary leiomyomatosis and renal cell carcinoma-associated renal cell carcinomas from kidney tumors without FH gene alteration
    Muller, Marie
    Guillaud-Bataille, Marine
    Salleron, Julia
    Genestie, Catherine
    Deveaux, Sophie
    Slama, Abdelhamid
    de Paillerets, Brigitte Bressac
    Richard, Stephane
    Benusiglio, Patrick R.
    Ferlicot, Sophie
    MODERN PATHOLOGY, 2018, 31 (06) : 974 - 983
  • [6] Immunohistochemistry for 2-Succinocysteine (2SC) and Fumarate Hydratase (FH) in Cutaneous Leiomyomas May Aid in Identification of Patients With HLRCC (Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome)
    Buelow, Benjamin
    Cohen, Jarish
    Nagymanyoki, Zoltan
    Frizzell, Norma
    Joseph, Nancy M.
    McCalmont, Timothy
    Garg, Karuna
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2016, 40 (07) : 982 - 988
  • [7] Immunohistochemistry for 2SC and FH in Cutaneous Leiomyomas May Aid in Identification of Patients With HLRCC (Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome)
    Buelow, Ben
    Cohen, Jarish
    Joseph, Nancy
    McCalmont, Timothy
    Garg, Karuna
    MODERN PATHOLOGY, 2015, 28 : 117A - 117A
  • [8] Immunohistochemistry for 2SC and FH in Cutaneous Leiomyomas May Aid in Identification of Patients With HLRCC (Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome)
    Buelow, Ben
    Cohen, Jarish
    Joseph, Nancy
    McCalmont, Timothy
    Garg, Karuna
    LABORATORY INVESTIGATION, 2015, 95 : 117A - 117A
  • [9] Loss of Fumarate Hydratase and Aberrant Protein Succination Detected With S-(2-Succino)-Cysteine Staining to Identify Patients With Multiple Cutaneous and Uterine Leiomyomatosis and Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome
    Llamas-Velasco, Mar
    Requena, Luis
    Adam, Julie
    Frizzell, Norma
    Hartmann, Arndt
    Mentzel, Thomas
    AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2016, 38 (12) : 887 - 891
  • [10] Validation of the Commercial Fumarate Hydratase (FH) and 2SC Antibodies for Immunohistochemistry in Diagnosing Molecularly Confirmed FH-Deficient Renal Cell Carcinoma
    Chang, Hsin-Yi
    Hang, Jen-Fan
    Chen, Paul
    Pan, Chin-Chen
    MODERN PATHOLOGY, 2022, 35 (SUPPL 2) : 579 - 580