Synthesis and characterizations of biocompatible polymers and carbon nanotubes-based hybrids for biomedical applications

被引:13
|
作者
Arumugam, Sivaranjani [1 ]
Ramamoorthy, Padmapriya [2 ]
Chakkarapani, Lakshmi Devi [3 ]
机构
[1] Bharath Inst Higher Educ & Res, Dept Chem, Chennai 600073, Tamil Nadu, India
[2] JIPMER, Dept Pharmacol, Pondicherry, India
[3] Ecole Polytech Fed Lausanne, Lab Electrochim Phys & Analyt, Sion, Switzerland
关键词
Bone tissue engineering; carbon nanotubes; hydroxyapatite; nanohybrids; polymers; DRUG-RELEASE; CHITOSAN; SCAFFOLDS; NANOPARTICLES; HYDROXYAPATITE; PROLIFERATION; POLYESTER; HYDROGELS; TOXICITY; GROWTH;
D O I
10.1080/00914037.2019.1616200
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
The outstanding physico-chemical properties of carbon nanotubes (CNTs) applied to rectify the problems in bone tissue engineering through enhancing cell proliferation, adhesion and viability, which lead to the improvement in bone replacement, growth and healing. Hence, in this study, biocompatible polymers functionalized with CNTs and then synthetic bone minerals i.e. hydroxyapatite has been stabilized onto CNTs-polymer matrixes. Structural morphology of the materials was analyzed by spectroscopic/microscopic analyses. The cytotoxic property of nanohybrids was examined on osteoblast-like MG-63 cells. The lack of significant cytotoxic effect of nanohybrids suggested that the nanohybrids are considered as promising candidates for bone tissue engineering applications.
引用
收藏
页码:786 / 797
页数:12
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