Inhibition of DKK1 activity is associated with increased osteoblast numbers and bone formation, reduced osteoclast activity and inhibition of tumor growth in the SCID-rab model for primary myeloma.

被引：0

|

作者：

Yaccoby, S ^{[1
]}

Ling, W ^{[1
]}

Saha, R ^{[1
]}

Zhan, FH ^{[1
]}

Walker, R ^{[1
]}

Tricot, G ^{[1
]}

Barlogie, B ^{[1
]}

Shaughnessy, JD ^{[1
]}

机构：

[1] Univ Arkansas Med Sci, Myeloma Inst Res & Therapy, Little Rock, AR 72205 USA

来源：

BLOOD | 2005年 / 106卷 / 11期

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D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

638

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页码：189A / 189A

页数：1

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[1] Blocking DKK1 activity in primary myeloma-bearing SCID-rab mice is associated with increased osteoblast activity and bone formation, and inhibition of tumor growth.
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[2] Anti-myeloma response to bortezomib is associated with increased osteoblast activity and bone formation in primary myelomatous SCID-rab mice.
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