Quantitative Assessment of Hyaline Cartilage Elasticity during Optical Clearing using Optical Coherence Elastography

被引：1

作者：

Liu, Chih-Hao ^{[1
]}

Singh, Manmohan ^{[1
]}

Li, Jiasong ^{[1
]}

Han, Zhaolong ^{[1
]}

Wu, Chen ^{[1
]}

Wang, Shang ^{[2
]}

Idugboe, Rita ^{[1
]}

Raghunathan, Raksha ^{[1
]}

Zakharov, Valery P. ^{[3
]}

Sobol, Emil N. ^{[4
]}

Tuchin, Valery V. ^{[3
,5
,6
]}

Twa, Michael ^{[7
]}

Larin, Kirill V. ^{[1
,3
,5
]}

机构：

[1] Univ Houston, Dept Biomed Engn, Houston, TX 77204 USA

[2] Baylor Coll Med, Dept Mol Physiol & Biophys, Houston, TX 77030 USA

[3] Samara State Aerosp Univ, Dept Elect Engn, Samara 443086, Russia

[4] Moscow MV Lomonosov State Univ, Dept Phys, Moscow 119991, Russia

[5] Saratov NG Chernyshevskii State Univ, Dept Opt & Biophoton, Saratov 410012, Russia

[6] Tomsk State Univ, Interdisciplinary Lab Biophoton, Tomsk 634050, Russia

[7] Univ Houston, Coll Optometry, Houston, TX 77204 USA

来源：

DYNAMICS AND FLUCTUATIONS IN BIOMEDICAL PHOTONICS XII | 2015年 / 9322卷

关键词：

Optical coherence elastography; Young's modulus; hyaline cartilage; optical clearing; GLUCOSE DIFFUSION; QUANTIFICATION; OCT; PORCINE; TISSUES;

D O I：

10.1117/12.2079854

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

We report the first study on using optical coherence elastography (OCE) to quantitatively monitor the elasticity change of the hyaline cartilage during the optical clearing administrated by glucose solution. The measurement of the elasticity is verified using uniaxial compression test, demonstrating the feasibility of using OCE to quantify the Young's modulus of the cartilage tissue. As the results, we found that the stiffness of the hyaline cartilage increases during the optical clearing of the tissue. This study might be potentially useful for the early detection of osteoarthritis disease.

引用

页数：9

共 50 条

[1] Quantitative Assessment of Hyaline Cartilage Elasticity During Optical Clearing Using Optical Coherence Elastography
Liu, Chih-Hao
Singh, Manmohan
Li, Jiasong
Han, Zhaolong
Wu, Chen
Wang, Shang
Idugboe, Rita
Raghunathan, Raksha
Sobol, Emil N.
Tuchin, Valery V.
Twa, Michael
Larin, Kirill V.
SOVREMENNYE TEHNOLOGII V MEDICINE, 2015, 7 (01) : 44 - 51
[2] Nonlinear characterization of elasticity using quantitative optical coherence elastography
Qiu, Yi
Zaki, Farzana R.
Chandra, Namas
Chester, Shawn A.
Liu, Xuan
BIOMEDICAL OPTICS EXPRESS, 2016, 7 (11): : 4702 - 4710
[3] Quantitative optical coherence elastography as an inverse elasticity problem
Dong, Li
Wijesinghe, Philip
Dantuono, James T.
Sampson, David D.
Munro, Peter R. T.
Kennedy, Brendan F.
Oberai, Assad A.
OPTICAL ELASTOGRAPHY AND TISSUE BIOMECHANICS III, 2016, 9710
[4] Elasticity Measurement of Nasal Cartilage as a Function of Temperature Using Optical Coherence Elastography
Liu, Chih-Hao
Skryabina, M. N.
Singh, Manmohan
Li, Jiasong
Wu, Chen
Sobol, E.
Larin, Kirill V.
OPTICAL ELASTOGRAPHY AND TISSUE BIOMECHANICS II, 2015, 9327
[5] Characterization of nonlinear elasticity for biological tissue using quantitative optical coherence elastography
Qiu, Yi
Zaki, Farzana R.
Chandra, Namas
Chester, Shawn A.
Liu, Xuan
OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICINE XXI, 2017, 10053
[6] Quantitative micro-elastography: imaging of tissue elasticity using compression optical coherence elastography
Kennedy, Kelsey M.
Chin, Lixin
McLaughlin, Robert A.
Latham, Bruce
Saunders, Christobel M.
Sampson, David D.
Kennedy, Brendan F.
SCIENTIFIC REPORTS, 2015, 5
[7] Quantitative micro-elastography: imaging of tissue elasticity using compression optical coherence elastography
Kelsey M. Kennedy
Lixin Chin
Robert A. McLaughlin
Bruce Latham
Christobel M. Saunders
David D. Sampson
Brendan F. Kennedy
Scientific Reports, 5
[8] Quantitative Compression Optical Coherence Elastography as an Inverse Elasticity Problem
Dong, Li
Wijesinghe, Philip
Dantuono, James T.
Sampson, David D.
Munro, Peter R. T.
Kennedy, Brendan F.
Oberai, Assad A.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 2016, 22 (03) : 277 - 287
[9] Quantitative assessment of corneal elasticity distribution after FS-LASIK using optical coherence elastography
Han, Xiao
Zhang, Yubao
Shi, Gang
Liu, Guo
Ai, Sizhu
Wang, Yidi
Zhang, Qin
He, Xingdao
JOURNAL OF BIOPHOTONICS, 2024, 17 (04)
[10] In situ assessment of lens elasticity with noncontact optical coherence elastography
Chen, Yulei
Ye, Shuling
Wang, Qingying
Shen, Meixiao
Lu, Fan
Qu, Jia
Zhu, Dexi
BIOMEDICAL OPTICS EXPRESS, 2022, 13 (12) : 6671 - 6681

← 1 2 3 4 5 →