Primary cutaneous aspergillosis complicated with invasive aspergillosis in an extremely preterm infant: Case report and literature review

被引：7
|
作者：
Stock, C. [1 ]
Veyrier, M. [1 ]
Magnin-Verschelde, S. [1 ]
Duband, S. [2 ]
Lavocat, M. -P. [1 ]
Teyssier, G. [1 ]
Berthelot, P. [3 ]
机构：
[1] Hop Nord St Priest Jarez, Ctr Hosp Univ St Etienne, Serv Reanimat Neonatale & Pediat, F-42270 St Priest En Jarez, France
[2] Ctr Hosp Univ St Etienne, Serv Anat & Cytol Pathol, F-42055 St Etienne 2, France
[3] Ctr Hosp Univ St Etienne, Serv Malad Infect, Unite Hyg Interhosp, F-42055 St Etienne 2, France
来源：
ARCHIVES DE PEDIATRIE | 2010年 / 17卷 / 10期
关键词：
PREMATURE-INFANT; AMPHOTERICIN-B; VORICONAZOLE;
D O I：
10.1016/j.arcped.2010.04.012
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Aspergillus is a ubiquitous fungus that can cause primary cutaneous aspergillosis in extremely low-birth-weight (E LAM) neonates, then be invasive and lead to death. ELBW neonates are particularly at risk because of decreased qualitative immune defenses and defects in the skin barrier. Broad-spectrum antimicrobial therapy and corticosteroids, often used in these patients, contribute to increased risk. We present a fatal case of primary cutaneous aspergillosis complicated with invasive aspergillosis, confirmed by autopsy, in an ELBW infant. The source of contamination was probably non-sterile disposable latex gloves used for neonatal care. The early recognition of this source led to its eviction for oilier hospitalized ELBW infants and no outbreak was observed. (C) 2010 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：1455 / 1459
页数：5
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