Rational design of potent factor VIIa inhibitors using quantum chemical methods

被引：0

作者：

Cheney, Daniel ^{[1
]}

Delucca, Indawati ^{[1
]}

Glunz, Peter ^{[1
]}

Jiang, Wen ^{[1
]}

Ladziata, Vladimir ^{[1
]}

Parkhurst, Brandon ^{[1
]}

Zhang, Yanfeng ^{[1
]}

Zou, Yan ^{[1
]}

Bozarth, Jeffrey ^{[1
]}

Luettgen, Joseph ^{[1
]}

Rendina, Alan ^{[1
]}

Mueller, Luciano ^{[2
]}

Wei, Anzhi ^{[2
]}

Newitt, John ^{[2
]}

Tamura, James ^{[2
]}

Seiffert, Dietmar ^{[1
]}

Wong, Pancras ^{[1
]}

Wexler, Ruth ^{[1
]}

Priestley, E. ^{[1
]}

机构：

[1] Bristol Myers Squibb, Res & Dev, Hopewell, NJ USA

[2] Bristol Myers Squibb, Res & Dev, Princeton, NJ USA

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2015年 / 249卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

169

引用

页数：1

共 50 条

[1] Discovery of potent neutral factor VIIa inhibitors
Wurtz, Nicholas R.
Parkhurst, Brandon L.
Jiang, Wen
DeLucca, Indawati
Zhang, Xiaojun
Cheney, Daniel
Rendina, Alan
Metzler, William
Wei, Anzhi
Luettgen, Joseph
Wong, Pancras
Seiffert, Dietmar
Wexler, Ruth R.
Priestley, E. Scott
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244
[2] Discovery and optimization of potent and selective tissue factor/factor VIIa inhibitors
Hirota, Shinsuke
Clark, Richard
Matsuura, Fumiyoshi
Kira, Kazunobu
Azuma, Hiroshi
Nagakura, Tadashi
Horizoe, Tatsuo
Tabata, Kimiyo
Kusano, Kazutomi
Omae, Takao
Inoue, Atsushi
Critchley, David
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 242
[3] Discovery of Phenylglycine Lactams as Potent Neutral Factor VIIa Inhibitors
Wurtz, Nicholas R.
Parkhurst, Brandon L.
Jiang, Wen
DeLucca, Indawati
Zhang, Xiaojun
Ladziata, Vladimir
Cheney, Daniel L.
Bozarth, Jeffrey R.
Rendina, Alan R.
Wei, Anzhi
Luettgen, Joseph M.
Wu, Yiming
Wong, Pancras C.
Seiffert, Dietmar A.
Wexler, Ruth R.
Priestley, E. Scott
ACS MEDICINAL CHEMISTRY LETTERS, 2016, 7 (12): : 1077 - 1081
[4] Design and Synthesis of Peptidomimetic Factor VIIa Inhibitors
Shiraishi, Takuya
Kadono, Shojiro
Haramura, Masayuki
Kodama, Hirofumi
Ono, Yoshiyuki
Iikura, Hitoshi
Esaki, Tohru
Koga, Takaki
Hattori, Kunihiro
Watanabe, Yoshiaki
Sakamoto, Akihisa
Yoshihashi, Kazutaka
Kitazawa, Takehisa
Esaki, Keiko
Ohta, Masateru
Sato, Haruhiko
Kozono, Toshiro
CHEMICAL & PHARMACEUTICAL BULLETIN, 2010, 58 (01) : 38 - 44
[5] Rational design of potent and selective inhibitors of Pseudomonas aeruginosa virulence factor Cif
Kitamura, Seiya
Hvorecny, Kelli
Madden, Dean
Hammock, Bruce
Morisseau, Christophe
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 250
[6] Quantum Chemical-Based Protocol for the Rational Design of Covalent Inhibitors
Schirmeister, Tanja
Kesselring, Jochen
Jung, Sascha
Schneider, Thomas H.
Weickert, Anastasia
Becker, Johannes
Lee, Wook
Bamberger, Denise
Wich, Peter R.
Distler, Ute
Tenzer, Stefan
Johe, Patrick
Hellmich, Ute A.
Engels, Bernd
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2016, 138 (27) : 8332 - 8335
[7] Potent 4-amino-5-azaindole factor VIIa inhibitors
Hu, Huiyong
Kolesnikov, Aleksandr
Riggs, Jennifer R.
Wesson, Kieron E.
Stephens, Robin
Leahy, Ellen M.
Shrader, William D.
Sprengeler, Paul A.
Green, Michael J.
Sanford, Ellen
Nguyen, Margaret
Gjerstad, Erik
Cabuslay, Ronnel
Young, Wendy B.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (17) : 4567 - 4570
[8] Rational Design of Potent Inhibitors of a Metallohydrolase Using a Fragment-Based Approach
Feder, Daniel
Mohd-Pahmi, Siti H.
Hussein, Waleed M.
Guddat, Luke W.
McGeary, Ross P.
Schenk, Gerhard
CHEMMEDCHEM, 2021, 16 (21) : 3342 - 3359
[9] Design of selective phenylglycine amide tissue factor/factor VIIa inhibitors
Zbinden, KG
Banner, DW
Ackermann, J
D'Arcy, A
Kirchhofer, D
Ji, YH
Tschopp, TB
Wallbaum, S
Weber, L
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (03) : 817 - 822
[10] Discovery of potent and selective biaryl derivatives as tissue factor/factor VIIa inhibitors through structure-based drug design
Chand, P
Kotian, PL
Dehghani, A
El-Kattan, Y
Lin, TH
Wu, MW
Rowland, RS
Raman, K
Bantia, S
Arnold, S
Babu, YS
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 229 : U153 - U154

← 1 2 3 4 5 →