Application of in vivo laser scanning microscope in dermatology

被引:0
|
作者
Ladermann, J [1 ]
Richter, H [1 ]
Otberg, N [1 ]
Lawrenz, F [1 ]
Blume-Peytavi, U [1 ]
Sterry, W [1 ]
机构
[1] Charite, Ctr Expt & Appl Cutaneous Physiol, Dept Dermatol, Berlin, Germany
来源
SARATOV FALL MEETING 2002: OPTICAL TECHNOLOGIES IN BIOPHYSICS AND MEDICINE IV | 2002年 / 5068卷
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D O I
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中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
The state of the art of in-vivo and in-vitro penetration measurements of topically applied substances is described. Only optical techniques represent online measuring methods based on the absorption or scattering properties of the topically applied substances. Laser scanning microscopy (LSM) has become a promising method for investigations in dermatology and skin physiology, after it was possible to analyze the skin surface on any body side in-vivo. In the present paper the application of a dermatological laser scanning microscope for penetration and distribution measurements of topically applied substances is described. The intercellular and follicular penetration pathways were studied.
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页码:1 / 9
页数:9
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