Equistatin and equinatoxin gene expression is influenced by environmental temperature in the sea anemone Actinia equina

被引:11
|
作者
O'Hara, Emily P. [1 ]
Caldwell, Gary S. [1 ]
Bythell, John [1 ]
机构
[1] Newcastle Univ, Sch Nat & Environm Sci, Ridley Bldg, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England
关键词
Climate change; Cnidaria; Toxin gene expression; Venom ecology; Venom variation; 28S RIBOSOMAL-RNA; REAL-TIME PCR; PROTEASE INHIBITORS; METABOLIC COST; SOUTH-AFRICA; VENOM; VIRIDIS; POTATO; TOXIN; CELLS;
D O I
10.1016/j.toxicon.2018.08.004
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
We examined the gene expression levels of equinatoxin and equistatin in the sea anemone Actinia equina, when reared at varying environmental temperatures for five months. Both genes were significantly downregulated at 10 degrees C compared to 16 degrees C but showed no significant change at 22 degrees C. This provides the first evidence of an effect of temperature on gene expression, but with no effect of increasing temperatures such as those predicted due to climate change.
引用
收藏
页码:12 / 16
页数:5
相关论文
共 50 条
  • [1] Cardiovascular effects of equinatoxin III from the sea anemone Actinia equina (L.)
    Suput, D
    Frangez, R
    Bunc, M
    TOXICON, 2001, 39 (09) : 1421 - 1427
  • [2] Equistatin, a protease inhibitor from the sea anemone Actinia equina, is composed of three structural and functional domains
    Strukelj, B
    Lenarcic, B
    Gruden, K
    Pungercar, J
    Rogelj, B
    Turk, V
    Bosch, D
    Jongsma, MA
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000, 269 (03) : 732 - 736
  • [3] THE ACTION OF EQUINATOXIN, A PEPTIDE FROM THE VENOM OF THE SEA-ANEMONE, ACTINIA-EQUINA, ON THE ISOLATED LUNG
    LAFRANCONI, WM
    FERLAN, I
    RUSSELL, FE
    HUXTABLE, RJ
    TOXICON, 1984, 22 (03) : 347 - 352
  • [4] THE CYTOTOXIC AND CYTOLYTIC ACTIVITY OF EQUINATOXIN-II FROM THE SEA-ANEMONE ACTINIA-EQUINA
    BATISTA, U
    MACEK, P
    SEDMAK, B
    CELL BIOLOGY INTERNATIONAL REPORTS, 1990, 14 (11) : 1013 - 1024
  • [5] OCCURRENCE OF CATECHOLAMINES IN SEA ANEMONE ACTINIA EQUINA
    CARLYLE, RF
    BRITISH JOURNAL OF PHARMACOLOGY, 1969, 36 (01) : P182 - &
  • [6] EFFECT OF SERUM ON THE CYTOTOXIC ACTIVITY OF EQUINATOXIN-II FROM THE SEA-ANEMONE ACTINIA EQUINA L
    BATISTA, U
    SEDMAK, B
    MACEK, P
    TOXICON, 1987, 25 (04) : 364 - 364
  • [7] CHEMICAL MODIFICATION OF EQUINATOXIN-II, A POTENT CYTOLYSIN FROM THE SEA-ANEMONE ACTINIA-EQUINA
    TURK, T
    MACEK, P
    GUBENSEK, F
    TOXICON, 1988, 26 (01) : 45 - 45
  • [8] SEA-ANEMONE (ACTINIA-EQUINA) MYOSIN
    KANZAWA, N
    SATO, O
    TAKANOOHMURO, H
    MARUYAMA, K
    COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 1993, 104 (03): : 509 - 514
  • [9] Crystal structure of the soluble form of equinatoxin II, a pore-forming toxin from the sea anemone Actinia equina
    Athanasiadis, A
    Anderluh, G
    Macek, P
    Turk, D
    STRUCTURE, 2001, 9 (04) : 341 - 346
  • [10] CHEMICAL MODIFICATION OF EQUINATOXIN II, A LETHAL AND CYTOLYTIC TOXIN FROM THE SEA-ANEMONE ACTINIA-EQUINA L
    TURK, T
    MACEK, P
    GUBENSEK, F
    TOXICON, 1989, 27 (03) : 375 - 384