Experimental Study of the Effects of Dietressa, a New Weight-Reducing Drug

被引:2
|
作者
Kheyfets, I. A. [1 ]
Bugaeva, L. I.
Vorob'eva, T. M.
Dugina, J. L.
Lebedeva, S. A.
Petrov, V. I.
Sergeeva, S. A.
Epstein, O. I.
机构
[1] Mat Med Holding, Moscow, Russia
关键词
Dietressa; cannabinoid receptors; obesity; sibutramine; self-stimulation; OBESITY; HEALTH; RISK; LIFE;
D O I
10.1007/s10517-012-1518-x
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The capacity of a new drug containing ultra-low doses of antibodies to cannabinoid receptor type 1 (Dietressa) to reduce body weight gain in mice on a high-calorie diet was evaluated, possible mechanisms of drug action were analyzed, and its safety (abuse potential in the reaction of self-stimulation) was evaluated. Dietressa was not inferior to sibutramine in reducing body weight gain in mice and exhibited no abuse potential.
引用
收藏
页码:321 / 324
页数:4
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