BEYOND DXA: ADVANCES IN CLINICAL APPLICATIONS OF NEW BONE IMAGING TECHNOLOGY

被引:15
|
作者
Pawlowska, Monika [1 ]
Bilezikian, John P. [2 ]
机构
[1] Univ British Columbia, Dept Med, Div Endocrinol, Vancouver, BC, Canada
[2] Columbia Univ, Coll Phys & Surg, Dept Med, Metab Bone Dis Unit,Div Endocrinol, New York, NY USA
关键词
QUANTITATIVE COMPUTED-TOMOGRAPHY; TYPE-2; DIABETES-MELLITUS; CHINESE-AMERICAN WOMEN; IN-VIVO ASSESSMENT; PRIMARY HYPERPARATHYROIDISM; TRABECULAR BONE; POSTMENOPAUSAL WOMEN; MINERAL DENSITY; FRACTURE RISK; FRAGILITY FRACTURES;
D O I
10.4158/EP151019.RA
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Dual-energy X-ray absorptiometry (DXA) is generally a very useful tool for assessing bone mineral density (BMD) and fracture risk. However, observational studies have shown that in certain instances, BMD as measured by DXA systematically over-or underestimates fracture risk. We herein describe the clinical conundrums encountered when assessing fracture risk by DXA in patients with primary hyperparathyroidism or type 2 diabetes and those of Chinese ethnicity. Furthermore, we discuss how advanced imaging technology that examines skeletal microarchitecture is furthering our understanding of fracture risk in these clinical situations.
引用
收藏
页码:990 / 998
页数:9
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