SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW 2-(4-METHYLBENZOTHIAZOLE-2′-YL AMINO)-4-(2-CHLOROPHENYL THIOUREIDO)-6-(SUBSTITUTED THIOUREIDO)-1,3,5-TRIAZINES

被引:0
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作者
Sareen, V. [2 ]
Khatri, V. [2 ]
Jain, P. [2 ]
Sharma, K. [1 ]
机构
[1] RL Saharia Govt PG Coll, Dept Chem, Jaipur, Rajasthan, India
[2] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India
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中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
2,4,6-trichloro-1,3,5-triazine has been reacted selectively with nucleophilic reagents, 2-amino-4-methylbenzothiazole, 2-chlorophenyl thiourea and different substituted thioureas to give 2-(4-methylbenzothiazol-2'-yl amino)-4-(2-chlorophenyl-thioureido)-6-(substituted thioureido)-1,3,5-triazines (IV). The structure of all these compounds have been confirmed by their IR, (1)H NMR, (19)F NMR, mass spectral data and elemental analysis. These compounds show antibacterial activity against S. aureus, S. faecalis, E. coli and E. cloacae and fungicidal activity against Alternaria alternata, Aspergillus niger and Macrophomina.
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页码:91 / 92
页数:2
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