Is large birth weight associated with asthma risk in early childhood?

被引：10
|
作者：
To, Teresa [1 ,2 ,3 ,4 ]
Guan, Jun [4 ]
Wang, Chengning [1 ]
Radhakrishnan, Dhenuka [1 ]
McLimont, Susan [1 ]
Latycheva, Oxana [5 ]
Gershon, Andrea S. [1 ,3 ,4 ,6 ]
机构：
[1] Hosp Sick Children, Toronto, ON M5G 1X8, Canada
[2] Dalla Lana Sch Publ Hlth, Toronto, ON, Canada
[3] Univ Toronto, Dept Hlth Policy Management & Evaluat, Toronto, ON, Canada
[4] Inst Clin Evaluat Sci, Toronto, ON, Canada
[5] Asthma Soc Canada, Toronto, ON, Canada
[6] Sunnybrook Hlth Sci Ctr, Dept Med, Toronto, ON M4N 3M5, Canada
来源：
ARCHIVES OF DISEASE IN CHILDHOOD | 2012年 / 97卷 / 02期
基金：
加拿大健康研究院;
关键词：
COMPLEX CHRONIC CONDITIONS; POPULATION-BASED COHORT; FETAL-GROWTH; YOUNG-ADULTS; HAY-FEVER; ATOPY; CHILDREN; ONTARIO; MARKERS; SIZE;
D O I：
10.1136/adc.2010.187047
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Objective To determine the association between large birth weight and the risk of developing asthma in early childhood. Methods All single live births (n = 687 194) born in Ontario between 1 April 1995 and 31 March 2001 were followed until their sixth birthday. Their birth weight was categorised as low (<2.5 kg), normal (2.5-4.5 kg), large (4.6-6.5 kg) or extremely large (>6.5 kg). Poisson regression analysis was used. Results Compared with normal-birth-weight infants, large-birth-weight infants (2.3% of total) had a slightly lower risk of developing asthma by age 6 after adjusting for confounders (adjusted RR 0.90, 95% CI 0.86 to 0.93). There was a trend towards increased risk of asthma among extremely large-birth-weight infants (RR 1.21, 95% CI 0.67 to 2.19). Conclusions Contrary to previous reports, large birth weight was associated with a lower risk for asthma. Instead, a trend towards increased risk of asthma was observed among extremely large-birth-weight infants and interventions to reduce the incidence of extreme large birth weight may help reduce the risk of asthma.
引用
收藏
页码：169 / 171
页数：3
相关论文
共 50 条
  • [1] Is Large Birth Weight Associated With Asthma Risk In Early Childhood?
    To, T.
    Guan, J.
    Wang, C.
    Gershon, A.
    Radhakrishnan, D.
    McLimont, S.
    Raut, R.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2010, 181
  • [2] Low Birth Weight is a Risk for Early Atherosclerosis in Childhood
    Aydin, Akyuz
    Alpsoy, Seref
    Akkoyun, Dursun Cayan
    Nalbantoglu, Burcin
    Topcu, Birol
    Ozdilek, Burcu
    Donma, Mustafa Metin
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2013, 62 (18) : C38 - C39
  • [3] Impact of low birth weight on early childhood asthma in the United States
    Brooks, AM
    Byrd, RS
    Weitzman, M
    Auinger, P
    McBride, JT
    ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE, 2001, 155 (03): : 401 - 406
  • [4] The Association of Birth Weight with Cardiovascular Risk Factors in Early Childhood
    Dogan, Melih Timucin
    Duksal, Fatma
    Gultekin, Asim
    GAZI MEDICAL JOURNAL, 2021, 32 (2A): : 299 - 302
  • [5] Early-life weight gain is associated with asthma in childhood
    Ho, Chia-Hua
    Gau, Chun-Chun
    Lee, Wan-Fang
    Fang, Hsin
    Lin, Ching-Hua
    Chu, Chun-Hui
    Huang, Yin-Shan
    Huang, Yu-Wen
    Huang, Hsin-Yi
    Tsai, Hui-Ju
    Yao, Tsung-Chieh
    WORLD ALLERGY ORGANIZATION JOURNAL, 2022, 15 (08):
  • [6] Early Life Weight Gain and Development of Childhood Asthma in a Prospective Birth Cohort
    Tsai, Hui-Ju
    Wang, Guoying
    Hong, Xiumei
    Yao, Tsung-Chieh
    Ji, Yuelong
    Radovick, Sally
    Ji, Hongkai
    Cheng, Tina L.
    Wang, Xiaobin
    ANNALS OF THE AMERICAN THORACIC SOCIETY, 2018, 15 (10) : 1197 - 1204
  • [7] Early Life Weight Gain and Development of Childhood Asthma in a Prospective Birth Cohort
    Tsai, Hui-Ju
    Wang, Guoying
    Hong, Xiumei
    Ji, Yuelong
    Wang, Xiaobin
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2018, 141 (02) : AB194 - AB194
  • [8] Early Life Intestinal Metabolites Are Associated with Risk of Childhood Asthma
    Lee-Sarwar, K.
    Kelly, R. S.
    Lasky-Su, J. A.
    Zeiger, R. S.
    O'Connor, G. T.
    Sandel, M.
    Bacharier, L. B.
    Laranjo, N.
    Gold, D. R.
    Weiss, S. T.
    Litonjua, A. A.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2018, 197
  • [9] Birth weight for gestational age and the risk of asthma in childhood and adolescence: a retrospective cohort study
    Carter, Jillian H.
    Woolcott, Christy G.
    Liu, Lihui
    Kuhle, Stefan
    ARCHIVES OF DISEASE IN CHILDHOOD, 2019, 104 (02) : 179 - 183
  • [10] Evaluation of possible associated factors for early childhood caries: are preterm birth and birth weight related?
    Selen, Merve Bilmez
    Demir, Pinar
    Inceoglu, Feyza
    BMC ORAL HEALTH, 2024, 24 (01)
12345